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Course 2 - Dermatology > Psoriasis > Flashcards

Psoriasis Flashcards

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Dermatology Board Prep flashcards
1
Q

epi of psoriasis

A

2% of world

bimodal pattern (childhood, adulthood)

northern european descent

mild, moderate, severe based on % of body affected

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2
Q

psoriatic plaque morphology

A

well-demarcated circular, oval, or polycyclic erythematous plauqes that are symmetric in distribution

very thick (micaceous) and silvery scales

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3
Q

distribution of psoriasis

A

scalp, elbows and knees

lesions can last from months to years in the same location

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4
Q

what is auspitz sign?

A

removal of scale result in pinpoint bleeding, suggesting dianosis

scraping will raise bright white or silvery scales

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5
Q

what is this a presentation of?

A

Koebner phenomena

trauma-induced psoriasis

can interpret as slow healing wounds

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6
Q

what dermatitis co-exist with psoriasis

A

seborrheic dermatitis

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7
Q

psoriatic nail changes can be seen in absence of cutaneous involvement

A

T

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8
Q

what changes are seen in psoriatic nail disease

A

nail pitting

onycholysis (lifting of distal nail plate)

splinter hemorrhages

subungual hyperkeratosis

leukonychia

oil drop changes (red-brown discoloration)

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9
Q

what is inverse pattern of psoriasis

A

intertriginous areas of body

(axillae, groin, genitals, submammary area)

erythematous and well-demarcated but lack classic scale

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10
Q

how is scalp psoriasis treated

A

topical descaling agents such as salicylic acid or corticosteroids

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11
Q

what is this a presentation of?

A

pustular psoriasis

widespread erythematous, sterile pustules

palmar and plantar involvement

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12
Q

increased risk for psoriasis patients

A

CV disease (MI, PE, cerbrovascular accidents)

screen for diabetes, cholesterol, hypertension, obesity, smoking

chronic renal disease

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13
Q

Tx for psoriasis

A

IV light therapy

<10% BSA involvement: topical (retinoid, corticosteroid, vit D analog, topical tar, anthralin)

>10% BSA: systemic (methotrexate, mycophenolate mofetil, cyclosporine, tacrolimus, acitretin)

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14
Q

what is this a presentation of?

A

pityriasis rosea

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15
Q

describe pityriasis

A

discrete oval, erythematous, scaly plauqes and patches oriented along skin cleavage lines

most commonly on trunk and upper extremities

face palms, soles are usually spared

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16
Q

what is this a presentation of?

A

herald patch

solitary, scaly, pink or flesh-colored plaque

17
Q

speculated etiology of pityriasis rosea

A

associated with systemic reactivation of human herpes virus 6 and 7

18
Q

what pattern does pityriasis rosea present in?

A

begin with herald patch (truncal), with fine collarette of scale, patches and plaques form along skin fold lines on trunk

19
Q

what is this a presentation of?

A

lichen planus

20
Q

describe the pathophysiology of lichen planus

A

autoreactive T lymphocytes attack basal kertinocytes in skin, mucous membranes, hair follicles, and/or nail units

unclear etiology

21
Q

presentation of lichen planus

A

pruritic, flat-topped, pink to purple papules that are localized most commonly along the volar wrists, shins, presacral area, and hands

22
Q

what has been associated with cause of lichen planus?

A

hep b vaccination

medications causing lichen planus-like eruption

23
Q

what phenomenon is a hallmark of lichen planus (same for psoriasis)

A

Koebner phenomenin

24
Q

what is this a presentation of?

A

lichen planus

25
Q

describe mucous membrane involvement of lichen planus

A

lacy, net-like, white plaques with violaceous base on tongue or buccal mucosa

26
Q

Tx of lichen planus

A

withdraw potential offending medication

antihistamines for pruritus

systemic corticosteroids

metronidazole

systemic retinoids

phototherapy

27
Q

what is this a presentation of?

A

pityriasis rubra pilaris (PRP)

acute cutaneous eription accompanied by pruritus and/or pain

follicular papules on erythematous base coalescing to form large orange-red plauqes but islands of sparing

commonly begin on scalp, rapidly spread in craniocaudal direction

28
Q

what is this a presentation of?

A

erythroderma

diffuse redness of skin >90% of body surface

29
Q

causes of erythroderma

A

psoriasis, atopic dermatitis, idiopathic erythroderma, cutaneous T-cell lymphoma, drugs

30
Q

what can induce erythroderma?

A

drugs such as allopurinol, ampicillin, omeprazole, vancomycin

Course 2 - Dermatology (11 decks)

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