Psoriasis Flashcards
Diseases associated with psoriasis
Psoriatic arthritis (PsA)
Inflammatory bowel disease (IBD)
Coronary Artery Disease (CAD)
Psoriasis two major mechanisms
Hyperproliferation and abnormal differentiation of the epidermis
Immune mediated mechanisms (T-lymphocytes)
Factors contributing to psoriasis
Cold weather Stress Obesity Alcohol and smoking Koebner Phenomenon Medications
Koebner Phenomenon
Lesions develop at repetitive sites of injury
Drugs that trigger psoriasis
NSAIDs Lithium Carbonate Beta-Blockes Antimalarials ACE Inhibitors TCNs and Interferons
Auspitz sign
Punctuated bleeding from removing the top layer of a psoriasis lesion
Common sites of psoriasis
Scalp Trunk Back Elbows and Knees Nails
Most common form of psoriasis
Plaque Psoriasis
“Dew-drop-like” lesions in children or young adults
Guttate Psoriasis
What precedes the onset of guttate psoriasis?
Group A beta-hemolytic strep infection
When neutrophils in the stratum corneum are large enough to be apparent clinically.
Pustular psoriasis.
Locations where acute pustular psoriasis occurs
Palms and soles of feet
Generalized psoriasis that covers nearly the entire surface area.
Erythrodermic Psoriasis
Comorbidities for psoriasis
Autoimmune diseases CVD Metabolic Syndrome Lymphoma, melanoma, and nonmelanoma skin cancer Depression/suicide Psychologic and emotional burden
