PSA Points

Question 1

NEB vs Inhaled

Answer 1

.

Question 2

Better taken at night?

Answer 2

Statin

Question 3

Differentiate between fluid challenge and maintenance

Answer 3

.

Question 4

Dose errors when reviewing medications

Answer 4

.

Question 5

Pioglitazone has potential to cause…

Answer 5

hypoglycaemia

Question 6

NSAIDs vs decreased HB

Answer 6

.

Question 7

Metformin vs Renal Impairment

Answer 7

.

Question 8

Causes of Urinary Retention

Answer 8

• Anticholinergics (antipsychotics, antidepressants)
• General Anaesthetics
• Alpha Agonists
• Benzodiazepines
• NSAIDs
• Calcium Channel Blockers
• Antihistamines
• Alcohol

Question 9

Monitor dehydration initially with BP improvement

Answer 9

.

Question 10

HRT can cause sodium and fluid retention, so measure…

Answer 10

Blood Pressure

Question 11

Increased ALT is not an indication to decrease/change statin dose if slight

Answer 11

.

Question 12

Cautiously increase dose of thyroxine, if needed, in presence of angina

Answer 12

.

Question 13

Dose is the major determinant of peak, interval is the major determinant of trough

Answer 13

.

Question 14

0.1% solution is…

Answer 14

1mg/mL

Question 15

Be aware of MR vs SR preparations

Answer 15

.

Question 16

NSAIDs can raise BP through salt and water retention

Answer 16

.

Question 17

Iron causes constipation

Answer 17

.

Question 18

Carbimazole - sore throat or fever = report to doctor

Answer 18

Neutropaenia and Agranulocytosis Risk

Question 19

Nifedipine - Vasodilation - ankle oedema

Answer 19

.

Question 20

Thiazides vs Lithium

Answer 20

Confusion and Ataxia

Question 21

FBC provides objective measurement of blood loss

Answer 21

.

Question 22

Digoxin has linear kinetics

Answer 22

Proportionate dosing change

Question 23

Treatment of oculogyric crisis/acute dystonia

Answer 23

5-10mg Procyclidine IV (antimuscarinic action)

Question 24

Always review electrolytes and previous fluid therapy before fluid prescription

Answer 24

.

Question 25

Trazodone

Answer 25

Serotonin antagonist and uptake inhibitor (SARI) used for the treatment of depression

Question 26

ACEi vs Severe PVD

Answer 26

.

Question 27

Opiates, Benzodiazepines, Trazodone vs Confusion

Answer 27

.

Question 28

Calcium Channel Blockers vs Heart Failure (specifically due to systolic dysfunction)

Answer 28

.

Question 29

ACEi + Aldosterone Inhibitor - hyperkalaemia

Answer 29

.

Question 30

For glucose control in diabetes look at when the sugars are highest and preemptively target that (use common sense)

Answer 30

.

Question 31

Check DH for competing medicines or potential drug interactions when infection

Answer 31

.

Question 32

Trimethoprim vs Methotrexate

Answer 32

.

Question 33

Eplerenone

Answer 33

Potassium sparing diuretic

Question 34

Both males and females should use contraception if on methotrexate

Answer 34

.

Question 35

Mirtazapine - abnormal dreams

Answer 35

.

Question 36

Thiazide diuretics (such as indapamide) - hypokalaemia

Answer 36

.

Question 37

Gemfibrozil vs Statin

Answer 37

Rhabdomyolysis

Question 38

Is the swallow safe in hypoglycaemia (for management)

Answer 38

.

Question 39

Stop statin and restart with a lower dose if the symptoms are severe or the creatinine increases over 5x baseline

Answer 39

.

Question 40

Do not increase drug dose if compliance is the issue

Answer 40

.

Question 41

Cyclizine is the antiemetic of choice for patients at risk of...

Answer 41

- Extrapyramidal SEs | - QT prolongation

Question 42

Shingles (vesicular rash with dermatomal distribution) treatment is...

Answer 42

Aciclovir (or equivalents) 800mg 5x daily

Question 43

Hyperchloraemic Metabolic Alkalosis (eg prolonged vomiting and dehydration) treated with...

Answer 43

0.9% sodium chloride as ideal resuscitation fluid

Question 44

Ciclosporin causes hyperkalaemia

Answer 44

.

Question 45

The maximum dose of citalopram in the elderly is...

Answer 45

20mg

Question 46

Prednisolone and alendronic acid are known to cause dyspepsia

Answer 46

.

Question 47

PPIs and alendronic acid are known to cause diarrhoea

Answer 47

.

Question 48

Amlodipine and Naproxen are known to cause ankle oedema

Answer 48

.

Question 49

Beta Blockers and Digoxin are known to cause bradycardia

Answer 49

.

Question 50

Prolonged therapy is advised for candidal infections during pregnancy

Answer 50

.

Question 51

Oral treatment of C. diff infection unless severe

Answer 51

.

Question 52

In DKA, short acting insulin preparations should be stopped but long acting preparations should be continued

Answer 52

.

Question 53

Always prescribe by the pain ladder

Answer 53

- Paracetamol - NSAID - Weak Opiate - Strong Opiate - Patches

Question 54

Regular monitoring of renal function is required while on ciclosporin

Answer 54

.

Question 55

Liraglutide (GLP-1 Analogue) frequently causes GI (nausea and vomiting) symptoms

Answer 55

.

Question 56

Tramadol and Fentanyl can precipitate serotonin syndrome

Answer 56

.

Question 57

Procyclidine is the treatment of choice for drug-induced parkinsonism

Answer 57

.

Question 58

Screen blood pressure for COCP + risk factors

Answer 58

.

Question 59

Starting Azathioprine

Answer 59

Check thiopurine methyltransferase activity

Question 60

Oxycodone - hepatic metabolism to inactive compounds - therefore good for strong analgesia and renal function

Answer 60

.

Question 61

Amiodarone should be withdrawn in thyrotoxicosis

Answer 61

.