PSA Points Flashcards
NEB vs Inhaled
.
Better taken at night?
Statin
Differentiate between fluid challenge and maintenance
.
Dose errors when reviewing medications
.
Pioglitazone has potential to cause…
hypoglycaemia
NSAIDs vs decreased HB
.
Metformin vs Renal Impairment
.
Causes of Urinary Retention
- Anticholinergics (antipsychotics, antidepressants)
- General Anaesthetics
- Alpha Agonists
- Benzodiazepines
- NSAIDs
- Calcium Channel Blockers
- Antihistamines
- Alcohol
Monitor dehydration initially with BP improvement
.
HRT can cause sodium and fluid retention, so measure…
Blood Pressure
Increased ALT is not an indication to decrease/change statin dose if slight
.
Cautiously increase dose of thyroxine, if needed, in presence of angina
.
Dose is the major determinant of peak, interval is the major determinant of trough
.
0.1% solution is…
1mg/mL
Be aware of MR vs SR preparations
.
NSAIDs can raise BP through salt and water retention
.
Iron causes constipation
.
Carbimazole - sore throat or fever = report to doctor
Neutropaenia and Agranulocytosis Risk
Nifedipine - Vasodilation - ankle oedema
.
Thiazides vs Lithium
Confusion and Ataxia
FBC provides objective measurement of blood loss
.
Digoxin has linear kinetics
Proportionate dosing change
Treatment of oculogyric crisis/acute dystonia
5-10mg Procyclidine IV (antimuscarinic action)
Always review electrolytes and previous fluid therapy before fluid prescription
.
Trazodone
Serotonin antagonist and uptake inhibitor (SARI) used for the treatment of depression
ACEi vs Severe PVD
.
Opiates, Benzodiazepines, Trazodone vs Confusion
.
Calcium Channel Blockers vs Heart Failure (specifically due to systolic dysfunction)
.
ACEi + Aldosterone Inhibitor - hyperkalaemia
.
For glucose control in diabetes look at when the sugars are highest and preemptively target that (use common sense)
.
Check DH for competing medicines or potential drug interactions when infection
.
Trimethoprim vs Methotrexate
.
Eplerenone
Potassium sparing diuretic
Both males and females should use contraception if on methotrexate
.
Mirtazapine - abnormal dreams
.
Thiazide diuretics (such as indapamide) - hypokalaemia
.
Gemfibrozil vs Statin
Rhabdomyolysis
Is the swallow safe in hypoglycaemia (for management)
.
Stop statin and restart with a lower dose if the symptoms are severe or the creatinine increases over 5x baseline
.
Do not increase drug dose if compliance is the issue
.
Cyclizine is the antiemetic of choice for patients at risk of…
- Extrapyramidal SEs
- QT prolongation
Shingles (vesicular rash with dermatomal distribution) treatment is…
Aciclovir (or equivalents) 800mg 5x daily
Hyperchloraemic Metabolic Alkalosis (eg prolonged vomiting and dehydration) treated with…
0.9% sodium chloride as ideal resuscitation fluid
Ciclosporin causes hyperkalaemia
.
The maximum dose of citalopram in the elderly is…
20mg
Prednisolone and alendronic acid are known to cause dyspepsia
.
PPIs and alendronic acid are known to cause diarrhoea
.
Amlodipine and Naproxen are known to cause ankle oedema
.
Beta Blockers and Digoxin are known to cause bradycardia
.
Prolonged therapy is advised for candidal infections during pregnancy
.
Oral treatment of C. diff infection unless severe
.
In DKA, short acting insulin preparations should be stopped but long acting preparations should be continued
.
Always prescribe by the pain ladder
- Paracetamol
- NSAID
- Weak Opiate
- Strong Opiate
- Patches
Regular monitoring of renal function is required while on ciclosporin
.
Liraglutide (GLP-1 Analogue) frequently causes GI (nausea and vomiting) symptoms
.
Tramadol and Fentanyl can precipitate serotonin syndrome
.
Procyclidine is the treatment of choice for drug-induced parkinsonism
.
Screen blood pressure for COCP + risk factors
.
Starting Azathioprine
Check thiopurine methyltransferase activity
Oxycodone - hepatic metabolism to inactive compounds - therefore good for strong analgesia and renal function
.
Amiodarone should be withdrawn in thyrotoxicosis
.