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Pharmacology > PSA Points > Flashcards

PSA Points Flashcards

1
Q

NEB vs Inhaled

A

.

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2
Q

Better taken at night?

A

Statin

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3
Q

Differentiate between fluid challenge and maintenance

A

.

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4
Q

Dose errors when reviewing medications

A

.

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5
Q

Pioglitazone has potential to cause…

A

hypoglycaemia

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6
Q

NSAIDs vs decreased HB

A

.

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7
Q

Metformin vs Renal Impairment

A

.

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8
Q

Causes of Urinary Retention

A
  • Anticholinergics (antipsychotics, antidepressants)
  • General Anaesthetics
  • Alpha Agonists
  • Benzodiazepines
  • NSAIDs
  • Calcium Channel Blockers
  • Antihistamines
  • Alcohol
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9
Q

Monitor dehydration initially with BP improvement

A

.

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10
Q

HRT can cause sodium and fluid retention, so measure…

A

Blood Pressure

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11
Q

Increased ALT is not an indication to decrease/change statin dose if slight

A

.

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12
Q

Cautiously increase dose of thyroxine, if needed, in presence of angina

A

.

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13
Q

Dose is the major determinant of peak, interval is the major determinant of trough

A

.

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14
Q

0.1% solution is…

A

1mg/mL

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15
Q

Be aware of MR vs SR preparations

A

.

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16
Q

NSAIDs can raise BP through salt and water retention

A

.

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17
Q

Iron causes constipation

A

.

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18
Q

Carbimazole - sore throat or fever = report to doctor

A

Neutropaenia and Agranulocytosis Risk

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19
Q

Nifedipine - Vasodilation - ankle oedema

A

.

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20
Q

Thiazides vs Lithium

A

Confusion and Ataxia

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21
Q

FBC provides objective measurement of blood loss

A

.

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22
Q

Digoxin has linear kinetics

A

Proportionate dosing change

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23
Q

Treatment of oculogyric crisis/acute dystonia

A

5-10mg Procyclidine IV (antimuscarinic action)

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24
Q

Always review electrolytes and previous fluid therapy before fluid prescription

A

.

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25
Q

Trazodone

A

Serotonin antagonist and uptake inhibitor (SARI) used for the treatment of depression

26
Q

ACEi vs Severe PVD

A

.

27
Q

Opiates, Benzodiazepines, Trazodone vs Confusion

A

.

28
Q

Calcium Channel Blockers vs Heart Failure (specifically due to systolic dysfunction)

A

.

29
Q

ACEi + Aldosterone Inhibitor - hyperkalaemia

A

.

30
Q

For glucose control in diabetes look at when the sugars are highest and preemptively target that (use common sense)

A

.

31
Q

Check DH for competing medicines or potential drug interactions when infection

A

.

32
Q

Trimethoprim vs Methotrexate

A

.

33
Q

Eplerenone

A

Potassium sparing diuretic

34
Q

Both males and females should use contraception if on methotrexate

A

.

35
Q

Mirtazapine - abnormal dreams

A

.

36
Q

Thiazide diuretics (such as indapamide) - hypokalaemia

A

.

37
Q

Gemfibrozil vs Statin

A

Rhabdomyolysis

38
Q

Is the swallow safe in hypoglycaemia (for management)

A

.

39
Q

Stop statin and restart with a lower dose if the symptoms are severe or the creatinine increases over 5x baseline

A

.

40
Q

Do not increase drug dose if compliance is the issue

A

.

41
Q

Cyclizine is the antiemetic of choice for patients at risk of…

A
  • Extrapyramidal SEs

- QT prolongation

42
Q

Shingles (vesicular rash with dermatomal distribution) treatment is…

A

Aciclovir (or equivalents) 800mg 5x daily

43
Q

Hyperchloraemic Metabolic Alkalosis (eg prolonged vomiting and dehydration) treated with…

A

0.9% sodium chloride as ideal resuscitation fluid

44
Q

Ciclosporin causes hyperkalaemia

A

.

45
Q

The maximum dose of citalopram in the elderly is…

A

20mg

46
Q

Prednisolone and alendronic acid are known to cause dyspepsia

A

.

47
Q

PPIs and alendronic acid are known to cause diarrhoea

A

.

48
Q

Amlodipine and Naproxen are known to cause ankle oedema

A

.

49
Q

Beta Blockers and Digoxin are known to cause bradycardia

A

.

50
Q

Prolonged therapy is advised for candidal infections during pregnancy

A

.

51
Q

Oral treatment of C. diff infection unless severe

A

.

52
Q

In DKA, short acting insulin preparations should be stopped but long acting preparations should be continued

A

.

53
Q

Always prescribe by the pain ladder

A
  • Paracetamol
  • NSAID
  • Weak Opiate
  • Strong Opiate
  • Patches
54
Q

Regular monitoring of renal function is required while on ciclosporin

A

.

55
Q

Liraglutide (GLP-1 Analogue) frequently causes GI (nausea and vomiting) symptoms

A

.

56
Q

Tramadol and Fentanyl can precipitate serotonin syndrome

A

.

57
Q

Procyclidine is the treatment of choice for drug-induced parkinsonism

A

.

58
Q

Screen blood pressure for COCP + risk factors

A

.

59
Q

Starting Azathioprine

A

Check thiopurine methyltransferase activity

60
Q

Oxycodone - hepatic metabolism to inactive compounds - therefore good for strong analgesia and renal function

A

.

61
Q

Amiodarone should be withdrawn in thyrotoxicosis

A

.

Pharmacology (16 decks)

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