Pruritus Flashcards
1
Q
define
A
itch
2
Q
mediators
A
chemicals
nerve transmission
CNS
3
Q
chemical mediators
A
histamine PGE2 ACh serotonin kallikrein IL-2 substance P tryptase
4
Q
nerve transmission
A
unmyelinated C fibres
5
Q
CNS mediators
A
opiates
6
Q
four types of pruritus
A
pruritoceptive
neuropathic
neurogenic
psychogenic
7
Q
define pruritoceptive
A
usually assocaited with inflammation or dryness in skin that triggers itch
8
Q
define neuropathic
A
damage to any of central or peripheral nerves causing itch
9
Q
define neurogenic
A
no evident damage to CNS but itch caused by effects of opiates on CNS
10
Q
define psychogenic
A
psychological cause with no pathology
11
Q
management
A
determine cause
anti-itch treatment
12
Q
anti-itch treatment
A
antihistamines emollients antidepressants phototherapy opiate antagonists