Protozoa Flashcards
Giardia spp. hosts
Mammals, birds, amphibians
What are the two main stages of the Giardia spp. lifestyle?
Cysts and trophozoites
Giardia duodenalis clinical signs
Usually none, malabsorption, diarrhea
Giardia duodenalis diagnosis
Fecal exam, ELISA
Giardia duodenalis treatment (dogs and cats)
Fenbendazole 50mg/kg SID for 5 days, can extend to 10 days
Giardia duodenalis treatment (+ infection, but asymptomatic)
Treat all animals in house once, DO NOT repeat treatment if asymptomatic
What organism causes feline tritrichomoniasis?
Tritrichomonas blagburni
Tritrichomonas blagburni characteristics
Forms pseudocysts, longitudinal binary fission
Feline tritrichomoniasis clinical signs
Chronic, large bowel diarrhea
Tritrichomonas blagburni transmission
Fecal-oral route, can survive outside host
Tritrichomonas blagburni diagnosis
Direct fecal smear, culture, PCR, colonic biopsy
Tritrichomonas blagburni treatment and control
No approved treatment, ronidazole and metronidazole have demonstrated efficacy
Keep infected cats away from other cats
Non-pathogenic trichomonas species
Pentratrichomonas hominis
Tritrichomonas canistomae, T. felistomae
Pentratrichomonas hominis host/location
mammals; cecum and colon
Tritrichomonas canistomae, T. felistomae host/location
dogs and cats; mouth
Characteristics of trypanosomes
Parasites of vertebrates (blood and tissue), usually transmitted by arthropod vector, most not pathogenic
Physical characteristics of trypanosomes
Kinetoplast
Pleomorphic
Cytoskeleton (with microtubules)
Single nucleus
Chagas disease
Trypanosoma cruzi in humans
American Trypanosomiasis
Trypanosoma cruzi in dogs, cats, possums, and racoons
Trypanosoma cruzi vector
Reduviid bug
Trypanosoma cruzi morphology (2 different stages)
Trypomastigote (subterminal kinetoplast) and amastigote
Trypanosoma cruzi infective stage
Metacyclic trypomastigote passed in feces of IH
Amastigotes
Form pseudocysts in host tissues
American Trypanosomiasis in dogs (distribution, deaths, transmission)
Sporting dogs (52%) and working dogs (13%), 50% acute deaths in dogs <1 yr, transmission in utero and via milk reported
American Trypanosomiasis in dogs acute phase
Trypomastigotes circulating in blood, fever, anorexia, lethargy, diarrhea
American Trypanosomiasis in dogs chronic phase
Trypomastigotes no longer circulating, congestive heart failure, arrhythmias, anemia, respiratory difficulty
Trypanosoma cruzi diagnosis
Serological testing (TESA blot, ELISA, IFA), blood smear, xenodiagnosis
Trypanosoma cruzi treatment
Most experimental, low efficacy, treatment over 2-3 months (benzidazole, ravuconazole)
Cystoisospora and Eimeria spp. general characteristics
Stenoxenous (narrow host range), worldwide distribution, organ specificity, monoxenous (parasitize 1 host)
Cystoisospora spp. physical characteristics
2 sporocysts/4 sporozoites each
Eimeria spp. physical characteristics
4 sporocysts/2 sporozoites each
Coccidia species
Cystoisospora and Eimeria spp.
Cystoisospora and Eimeria spp. reproduction
Schizogony (asexual) - multiple fission
Gamogony (sexual) - union of dissimilar gametes
Coccidia transmission
Ingestion of sporulated oocyst from contaminated soil, food, water, bedding, litter
Coccidia clinical signs (dogs and cats)
Occasional diarrhea, death in young animals, enteritis
Is coccidia zoonotic?
No!
How to control coccidia in environment
Promptly remove feces
Coccidia treatment
Lots of options Sulfadimexothime Furazolidone Amprolium Ponazuril
Which coccidia species is a spurious parasite (not a true parasite)?
Eimeria (usually dogs, but also cats)
Cryptosporidium spp. host/location
dogs (C. canis), cats (C. felis); small intestine