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Micro > Protozoa > Flashcards

Protozoa Flashcards

1
Q

Produces cytopathic effect of E. Histolytica

A

Cysteine proteases

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2
Q

Mediates adherence of entamoeba

A

Lectin

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3
Q

Flask shaped colon ulcers

Dysentery without fever

A

Amebic colitis

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4
Q

Most common extraintestinal form of entamoeba

Anchovy sauce aspirate

A

Amebic liver abscess

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5
Q

Ttt for cyst carrier state of entamoeba

A

Diloxanide furoate

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6
Q

Luminal agents for entamoeba

A

Diloxanide furoate
Iodoquinol
Paromomycin

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7
Q

Falling leaf motility

A

Giardia lamblia

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8
Q

Variant surface protein

A

Giardia lamblia

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9
Q

Villous flattening, disruption of cytoskeleton Ultimately leads to enterocyte apoptosis

A

Giardia

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10
Q

Excessive flatus
Foul smelling diarrhea
Chronic: steatorrhea

A

Giardia

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11
Q

Acid fast parasite autoinfection in IS pts, self limited nonbloody diarrhea

A

Cryptosporidium parvum

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12
Q

Ttt for crytosporidium

A

Nitazoxanide

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13
Q

Infective and diagnostic stage of cryptosporidium

A

Thick walled oocysts

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14
Q

Pear shaped flagellated trophozoites

A

Trichimonas vaginalis

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15
Q

Greenish vaginal discharge

A

Trichomoniasis

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16
Q

Strawberry cervix
Ectocervicitis
Punctate hemorrhage

A

Trichomoniasis

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17
Q

Ttt for trichomoniasis

A

Metronidazole 2 g

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18
Q

Transmitted thru anopheles

A

Plasmodium

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19
Q

Infective stage of plasmodium

A

Sporozoites

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20
Q

Diagnostic stage of plasmodium

A

Trophozoites (ring forms)

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21
Q

Provides immunity to malaria

A

RBC defects

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22
Q

Banana shaped gametocyte

A

P. falciparum

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23
Q

Large round gametocyte

A

P. vivax

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24
Q

Recurrence of symptoms after temp abatement 2-4 weeks

A

Recrudescence

Falciparum, malariae

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25
Q

Return of disease after cessation, reactivation of hypnozoites (1-6 months)

A

Relapse

Vivax, ovale

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26
Q

Benign quartan

A

P. malariae

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27
Q

Malignant tertian

A

P. falciparum

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28
Q

Highest yield in blood samples for plasmodium

A

During fever or 2-3 hrs after peak

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29
Q

Punctate granulations in RBC

A

Schuffner - ovale, vivax

30
Q

Coarse granulations in RBC

A

Maurer - falciparum

31
Q

Fine granulations in RBC

A

Ziemann - malariae

32
Q

Malarial or durck granulomas

A

Cerebral malaria

33
Q

Intravascular hemolysis
Massive hemoglobinuria
ARF

A

Blackwater fever

P. falciparum

34
Q

Septic shock due to plasmodium

A

Algid malaria

35
Q

Endemic areas for plasmodium

A

Palawan
Kalinga apayao
Ifugao
Agusan del sur

36
Q

Areas with Chloroquine resistant malaria

A

Palawan
Davao del norte
Compostela valley

37
Q

Tissue schizonticide (liver) and gametocide (blood)

A

Primaquine

38
Q

Blood schizonticide

A

Chloroquine

Quinine

39
Q

Sporonticide in mosquito

A

Proguanil

Pyrimethamine

40
Q

Ttt for Chloroquine resistant malariae

A

Mefloquine + doxycycline

41
Q

Eradication of hypnozoites

A

Primaquine

42
Q

Severe or pregnant

A

Chloroquine or quinine

43
Q

Vivax and ovale ttt

A

Chloroquine + primaquine

44
Q

Prophylaxis for plasmodium

A

Chloroquine

45
Q

Prophylactic for areas with chloroquine resistance

A

Malarone

Mefloquine

46
Q

Prophylaxis for MDR resistant falciparum

A

Doxycycline

47
Q

Definitive host: domestic cat

A

Toxoplasma gondii

48
Q

Preferred dx test for toxoplasmosis

A

IgM antibody

49
Q

Intracranial calcifications

A

Congenital toxoplasmosis

50
Q

Ttt for toxoplasmosis

A

Sulfadiazine + pyrimethamine

51
Q

Transmitted by reduviid bug (triatoma)

A

Trypanosoma cruzi

52
Q

Most often and severely affected tissue by t. Cruzi

A

Cardiac muscle

53
Q

Periorbital edema in acute chagas dse

A

Romana’s sign

54
Q

Ttt of chagas dse

A

Nifurtimox

55
Q

Dx stage of t. Cruzi and t. Bruceii

A

Trypomastigotes in blood

56
Q

Transmission by tsetse fly (glossina) bite

A

Trypanosoma brucei

57
Q

Remarkable antigenic variation

Cyclical fever spike every 2 weeks

A

Trypanosoma bruceii

58
Q

Enlargement of post cervical LN

A

Winterbottom’s sign

T. Bruceii

59
Q

Hyperesthesia in t. Bruceii

A

Kerandel’s sign

60
Q

Plasma cells with cytoplasmic immunoglobulin globules

A

Mott cells in t. Bruceii encephalitis

61
Q

Ttt for t. Bruceii

A

Suramin

Melarsoprol

62
Q

Transmission by bivalve molluscs and fish from red tide

A

Dinoflagellates

63
Q

Granulomatous amebic encephalitis

A

Acanthamoeba castellani

64
Q

Primary amebic meningoencephalitis

A

Naegleria fowleri

65
Q

Only ciliated protozoan to cause human dse - dysentery

Round based wide neck intestinal ulcers

A

Balantidium coli

66
Q

Transmitted by ixodes tick

A

Babesia microti

67
Q

Transmitted by sandfly

Infective promastigotes

A

Leishmania spp

68
Q

Ttt for leishmaniasis

A

Na stibogluconate (antimony)

69
Q 
Shellfish poisoning
Paralytic
Neurotoxic
Diarrhetic
Amnesic
A 
Shellfish poisoning
Paralytic: saxitoxin
Neurotoxic: brevetoxin
Diarrhetic: okadaic
Amnesic: domoic
70
Q

Dx stage entamoeba

A

Trophozoites

Mature & immature cysts

Micro (9 decks)

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