Proteins and their Building Blocks Flashcards
Protein structure is categorised into 4 levels…
Primary
Secondary
Tertiary
Quaternary
The linear sequence of amino acids determines the…
Properties of proteins
A molecule with charges, but no net charge is known as a…
Zwitterion
Peptide bonds join the terminal carbon of one amino acid to the…
N terminus (nitrogen) of another
Most amino acids are stereoisomeric, coming in a L or D forms. Proteins only contain the ? form
L for “living”
Peptide bonds are rigid due to a the formation of a… 🔒
Partial double bond
The CORN law states the order of the functional groups in L-form amino acids, assuming the hydrogen is…
Facing towards us
Chloramphenicol is an antibiotic, which works by mimicking the shape of a ? This enables it to bind to and thus inhibit the bacterial ribosome.
Peptide bond
Optical isomerism is important in the context of drug discovery and production because…
Different isomers can have very different effects
The ‘small’ amino acids are (5):
- Glycine
- Alanine
- Serine
- Threonine
- Cysteine
The charged/polar amino acids are (7):
Negatively charged: ➖ Aspartate ➖ Glutamate Polar: • Asparagine • Glutamine
Positively charged:
➕ Lysine
➕ Arginine
➕ Histidine
The hydrophobic amino acids are (4): 💧🙅♂️
- Valine
- Leucine / Isoleucine
- Methionine
- Proline
The aromatic amino acids are (3):
- Phenylalanine
- Tyrosine
- Tryptophan
The aromatic amino acids are also…
Hydrophobic
The largest amino acids are the…
Aromatic amino acids
