L24 Glycolysis Flashcards
Glycolysis is divided into 3 main phases…
- Investment
- Splitting
- Yield (payoff)
In step I of investment, glucose is phosphorylated by ? to form ?
Hexokinase to form G-6-P
Step II of investment is…
Isomerisation, where phosphoglucose-isomerase converts G-6-P into F-6-P
In step III of investment the molecule is then phosphorylated for a second time by…
Phosphofructokinase
The molecule present at the end of the investment phase is…
Fructose-1,6-bisphosphate
Fructose-1,6-bisphosphate splits with the help of an aldolase to form (2)…
- Dihydroxyacetone phosphate
2. Glyceraldehyde-3-phosphate (G-3-P)
Dihydroxyacetone phosphate is converted to G-3-P by…
Triosephosphate Isomerase (TPI / TIM)
The molecule present at the end of the splitting phase is…
Glyceraldehyde-3-phosphate (G-3-P) (2 per glucose)
In step VI, G-3-P is converted to 1,3-bisphosphoglycerate by…
G3P dehydrogenase (GAPDH)
Step VII (in the yield phase) is the first instance of…
Substrate-level phosphorylation (producing ATP)
Phosphoglycerate kinase removes one phosphate from 1,3-bisphosphoglycerate in order to…
Phosphorylate ADP, generating ATP!
In step VIII (yield phase) the phosphate is transferred to the central carbon, converting…
3-phosphoglycerate to 2-phosphoglycerate
3-phosphoglycerate is converted to 2-phosphoglycerate by…
Phosphoglyceromutase
In step IX (yield phase) what is removed to increase energy potential?
a) hydroxyl
b) water
c) phosphate
d) carbon
e) oxygen (O2)
b) water
The enzyme at step IX…
Enolase
