Proteins and their amino acids Flashcards
What does condensation of amino acids produce?
Peptide bonds
What do multiple peptide bonds make?
Peptide
What happens to chains of Amino acids in peptide bonds?
They fold up into proteins by non-covalent forces
What is a chaperone?
Helps fold the protein in a cell
What is the protein structure hierarchy? (4)
Primary structure - amino acids
Secondary structure - alpha-helix & beta pleated sheets
Tertiary structure - polypeptide chain
Quaternary structure - assembled subunits
What is an alpha helix? (2)
Most commonly occurring secondary structure
Right handed helix
What is key to an alpha helix?
hydrogen bonds
What is a Beta strand? (2)
Rely on other b strands for stability
Form sheets
What is key to the beta strand?
Hydrogen bonds
What is a tertiary structure made of?
alpha helical coils
What do hydrophobic interactions provide?
Stable core for folding proteins
What is the most common structural motif?
Beta - alpha - beta
How do proteins bind to ligands and substrates?
Using amino acid r groups, domains and motifs
How does DNA helices bind to DNA?
Protein motors
