proteins : amino acids Flashcards

1
Q

what is an amino acid ?

A

monomers of all proteins,and all amino acids have the same basic structure

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2
Q

what is an peptide bond ?

A

a bond formed when 2 amino acids are joined by a condensation reaction

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3
Q

what are proteins ?

A

large polymers comprised of long chains of amino acids

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4
Q

what are the function of proteins for animals ?

A

-form structural components of animals in particular e.g. muscles are made up of protein

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5
Q

what are the properties of proteins that provide a function in terms of enzymes ?

A

tendency to adopt specific shapes makes proteins important as enzymes (antibodies and some hormones)

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6
Q

what are properties of proteins that provide a function in terms of membranes ?

A

membranes have protein constituents that act as carriers and pores for active transport across the membrane and facilitated diffusion

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7
Q

why do animals and plants need amino acids ?

A

as amino acids are needed to make up proteins

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8
Q

what is meant by essential amino acids ?

A

essential amino acids are those that animals cannot synthesise themselves and must therefore obtain from their diet

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9
Q

why must animals obtain essential amino acids from their diet ?

A

animals can make some amino acids but others are essential and must be ingested because their bodies cannot produce them

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10
Q

how many naturally occurring (proteinogenic) amino acids are there in proteins and enzymes ?

A

20

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11
Q

how many amino acids are essential and must be taken in diet ?

A

8-10

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12
Q

how do plants make all the amino acids ?

A

if they have access to fixed nitrogen (such as nitrate )

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13
Q

what elements does each amino acid contain ?

A

carbon,hydrogen,oxyegn and nitrogen

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14
Q

what element does amino acid sometimes contain ?

A

sulphur

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15
Q

what does proteinogenic mean ?

A

they are only found in proteins

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16
Q

what does each protein chain of amino acids have (structure) ?

A

-has an amino acid group (-NH2) at one end
-a carboxyl (-COOH) group at the other end

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17
Q

draw the molecular structure of amino acids

A

find elsewhere :)

18
Q

what does the R group stand for ?

A

not for a particular element but different in each amino acid

19
Q

how can the R-group be complaicated ?

A

as in alanine = CH3
cysteine = CH3S

20
Q

what does almost all of amino acids end in ?

21
Q

what is the exception in terms of R-groups ? (ine)

A

those that have acidic R-groups e.g. aspartic acid and glutamic acid

22
Q

what can R-groups vary in ?

A

charge , size , polarity and whether is hydrophobic or hydrophilic

23
Q

why does R-group vary in properties ?

A

allows proteins to have a wide variety of shapes and functions in the body

24
Q

what shape does individual amino acids display and why ?

A

a tetrahedral shape due to the angles of the bonds between the atoms

25
what is the simplest of amino acid and what does possess ?
glycine which possesses a hydrogen atom
26
how does amino acids act as buffers ?
-accept H+ ions at low PH -release H+ ions at a high PH
27
what can amino acids act as and why ?
amphoteric as it can act as an acid and a base
28
what is a buffer ?
a buffer is a substance which helps to resist large changes in the pH
29
what are amino acids joined together by ?
covalent bonds called peptide bonds
30
what does making a peptide bond involve ?
a condensation reaction
31
what does breaking a peptide bond involve ?
a hydrolysis (reaction)
32
what does enzymes do to this reaction ?
catalyses them
33
what does protease enzymes do in the intestines ?
- break peptide bonds during digestion - break down protein hormones so that their effects are not permanent
34
what happens when 2 amino acids join together ?
they form a polypeptide
35
when joining a longer chain of amino acids it forms ..
polypeptide bonds
36
what does a protein consists (in terms of polypetide chains) ?
consists of single polypeptide chains or more than one chain together
37
draw a peptide molecule
find elsewhere :)
38
why does peptide bonds have properties of a double bond even though it is a single bond ?
due to the electron arrangement around the bond - this means that the bond is shorter than a conventional C-N bond
39
what makes a polypeptide chain relatively stiff and rigid ?
the fact that it inhibits rotation around the peptide bond
40
what test is used to detect peptide bonds and why ? (3)
biuret test - as it detects the presence of peptide bonds rather than proteins - small polypeptides may not give a positive result even if present