Proteins

Question 1

Out of total dry body weight, fraction made up of proteins?

Answer 1

3/4

Question 2

Peptide bond is formed when

Answer 2

Alpha carboxyl group of one aa reacts with alpha amino group to form a CONH bridge

Question 3

Primarstructure maintained by … bonds of peptide linkages

Answer 3

Covalent

Question 4

In secondary structure, which type of bond forms between peptide bonds

Answer 4

Hydrogen bonds

Question 5

Alpha helix structure

Answer 5

Alpha helix structure, polypeptide backbone. Side chain extended outwards

Question 6

Beta pleated sheets

Answer 6

Formed when two polypeptides(or more) line up side by side

Question 7

Tertiary structures reveals what information about proteins

Answer 7

Biological functions of proteins and their evolutionary origin

Question 8

Denaturation agents ? 4 in number

Answer 8

Ph
Temperature
Ionic strength
Solubility

Question 9

Interactions stabilizing tertiary structure

Answer 9

Hydrogen bonds
Ionic bonds
Disulphide bridges
Hydrophobic interactions

Thus, final shape determined by a variety of bonding interactions between the side chains on the amino acids

Question 10

Tertiary structure types

Answer 10

Globular

Fibrous

Question 11

What is the the domain of a protein

Answer 11

Fundamental units of tertiary structure.
‘Each domain containing an individual hydrophobic core built from secondary structural units connected by loop regions)

Generally contribute to the overall role of a protein

Question 12

Quarternary structure described

Answer 12

When more than one polypeptide form a functional protein complex held together by non covalent interactions

Question 13

Two main misfolding diseases(proteopathies)

Answer 13

Prions(Gain of toxic activity)

Amyloids(Loss of biological function)