protein translation and post-translational modification Flashcards
prokaryotes versus eukaryotes: explain why some antibiotics inhibit protein synthesis in prokaryotes but not eukaryotes
1
Q
how do antibiotics inhibit prokaryotic protein synthesis
A
exploit differences in ribosome (70S vs 80S)
2
Q
what do antibiotics inhibit
A
inhibit initiation, aa-tRNA binding, translocation, peptidyl transferase and cause early termination