PROTEIN STRUCTURE Flashcards

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1
Q

what is a protein?

A

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues

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2
Q

what are the 7 functions of proteins?

A
contractile
storage
structural
defence
signalling
transport
enzymes
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3
Q

what is structural?

A

things such as hair, horns, feathers

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4
Q

what is the cytoskeleton?

A

a microscopic network of protein filaments and tubules in the cytoplasm of many living cells, giving them shape and coherence/rigidity

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5
Q

what is storage?

A

this is the sources of amino acids, such as egg whites and milk

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6
Q

what does proteins defence include?

A

antibodies, blood clotting and WBC

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7
Q

what does a signalling protein do?

A

produces receptors and hormones, such as insulin, that give negative feedback and trigger a response

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8
Q

examples of protein transport…

A

membrane channels, blood proteins

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9
Q

what is an enzyme?

A

a catalyst substance that helps speed up a chemical reaction

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10
Q

polymer

A

monomers (amino acids) joined together to form a chain

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11
Q

how many amino acids are there?

A

20

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12
Q

what 6 substances make up an amino acid?

A
oxygen
hydrogen
carbon
nitrogen
sulphur
variable side chain
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13
Q

what do amino acids consist of?

A

an amino group (NH2)
a carboxyl group (COOH)
R group (one of the 20 side chains)

these all attach to a central carbon atom

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14
Q

what is the purpose of the side chain?

A

this is the part of the molecule that determines the function of the protein, aka its properties

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15
Q

what are bonds between monomers called?

A

peptide bonds

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16
Q

what reacts to form a polypeptide?

A

an amino group and an acid (the carboxyl group)

17
Q

what is a polypeptide?

A

many peptides joined together

18
Q

what is a peptide?

A

a compound consisting of two or more amino acids linked in a chain

19
Q

what is the primary structure?

A

the unique sequence of amino acids that form the polypeptide (the order of amino’s basically)

20
Q

what is the secondary structure?

A

the specific coiling or folding of the polypeptide chain

21
Q

what are the 2 types of secondary structure?

A

the alpha helix

the beta pleated sheets

22
Q

what is the tertiary structure?

A

this is the overall 3D structure of the polypeptide

23
Q

how is the tertiary structure held together?

A

by either: ionic bonding, disulfide bonding or hydrogen bonds

24
Q

What are the different hydro reactions?

A

hydrophilic and hydrophobic

attraction and repulsion

25
Q

many helix’s = ?

A

helices

26
Q

what is a hydrophobic interaction?

A

an insoluble mixture

27
Q

what is a hydrogen bond made up of?

A

H + O2

28
Q

what is a disulphide bond?

A

strong interchangeable bonds

29
Q

what are ionic bonds made of?

A

charges

30
Q

what is the quaternary structure?

A

the association of 2 or more polypeptide chains

31
Q

name 3 examples of quaternary polypeptides

A

insulin (12 chains)
collagen (3 chains)
haemoglobin (4 chains)

32
Q

basic analogy of protein structure

A

think of it as a necklace of amino acid beads

which often fold up into a ball