protein structure Flashcards

primary structure: summarise the reaction by which amino acids are joined together, sketch a trimeric peptide and identify the amino terminus, carboxyl terminus and side chains

1
Q

define protein

A

organic compound with 1 or more amino acid chains

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2
Q

structure of amino acid

A

H2N-C(H)(R)-COOH; where R is a variable side chain, H2N is an amino group; COOH is carboxyl group and C is the a-carbon

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3
Q

non-polar R group

A

hydrophobic

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4
Q

glycine as example of non-polar R group

A

-H (not chiral)

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5
Q

proline as example of non-polar R group

A

-(CH2)3 bound to a-carbon and N+ (kinky)

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6
Q

what form are non-chiral amino acids in for stability

A

L-form

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7
Q

polar R group

A

hydrophilic

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8
Q

serine as example of polar R group

A

-CH2OH

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9
Q

threonine as example of polar R group

A

-CH(CH3)(OH)

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10
Q

tyrosine as example of polar R group

A

-CH2C(CH)4C(OH)

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11
Q

asparagine as example of polar R group

A

-CH2CONH2

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12
Q

cysteine as example of polar R group

A

-CH2SH

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13
Q

lysine as example of charged R group

A

-(CH2)4NH3+

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14
Q

arginine as example of charged R group

A

-(CH2)3NHC+(NH2)2

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15
Q

aspartate as example of charged R group

A

-CH2COO-

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16
Q

glutamate as example of charged R group

A

-(CH2)2COO-

17
Q

what does -ate confer

A

acid as proton donation

18
Q

what type of reaction forms a peptide bond

A

condensation (produces water)

19
Q

where does a peptide bond form

A

amino/carboxyl terminus: -C(O)N(H)-

20
Q

how is order increased with a peptide bond

A

no free rotation