protein structure Flashcards
amino acids
proteins are made from a specific sequence of amino acids
primary structure
amino acids are joined by polypeptide bonds, many amino acids are joined together to form a polypeptide chain, this sequence of amino acids is called the primary structure
secondary structure
polypeptide molecules twist into a helix or folded shape, the shape is stabilised by hydrogen bonds between peptide groups
tertiary structure
polypeptide chains fold due to attractions and repulsions between non-adjacent amino acid side chains
quaternary structure
is more than one polypeptide molecule
disulphide bonds
covalent linkages between sulfur containing side chains of cyteines and are very strong helping to stabilize the tertiary structure
why the 3D shape of proteins is critical
the shape of proteins create regions that interact with other molecules in a cell, the shape of the protein is complementary to the shape of its target molecule. The shape allows for two molecules to interact with high specificity
peptide hormones
example of protein, hormones regulate physiology and behaviour in a multicellular organism by facilitating communication between cells
peptide hormone and their shape purpose
the hormones bind to receptor proteins in the membrane and cytoplasm of target cells. The shape of the receptor protein is complementary to the shape of the hormone
antibody
provide protection against pathogens by binding to and neutralizing molecules called antigens found on the surface of pathogens
antibody and its shape importance
the shape of an antibody is complementary to the shape of an antigen