Protein digestion/absorption and within the diet. Flashcards
Where does protein digestion occur?
NOT IN MOUTH
- Stomach
- Proteases and proenzymes
- Pepsin from pepsinogen - Small Intestine
Protein breakdown in stomach?
- Proteins are denatured by hydrochloric acid
- Pepsin begins digestion
- 10–20% of digestion
Where does Undigested protein go?
-Feces
Problems with digestion
- Celiac disease (Gluten from wheat, rye and barley)
2. Cystic fibrosis
Is pepsinagin active or inactive?
Inactive
Protein digestion in small intestine?
Proteases and intestinal lining cells
Where are Amino acids and peptide absorbed?
Small intestine
What are Pancreatic Proteases?*
Arginine + lysine+ Phenylalanine + Tyrosine
Specific to individual bonds. Made in pancreas- used in small intestine.
What is the first step of pepsin when digesting proteins?
- break down the chains of amino acids
- Trypsin breaks the bonds of arginine and lysine.
- Chymotrypsin breaks the bond of Phenylalanine and tyrosine.
Carboxpeptidase?*
Phenylalanine + Arginine+ Lysine+ tyrosine
ability to clean off/slip off the terminal Amino Acids
Dipeptidase?*
Arginine+ lysine+ phenylalanine
comes from small intestine
Tyrosine is connected to?*
Arginine
Chymotrypsin is connected?*
Phenylalanine
Protein synthesis
-Directed by cellular DNA
Amino Acid assembled in specific sequence
Draws on Amino Acid pool as needed
Synthesis of nonprotein molecules
Precursors:
- Neurotransmitters
- Vitamins (niacin (nonessential)
- DNA
- RNA
- melanin
- histamine
- glucose