Protein action Flashcards
a) How can monoclonal antibodies be produced
b) What are the defining features of aspartyl proteases
c) How many immunoglobulin domains does each IgG molecule have
d) What proteases contain zinc
e) What does antigen binding specificity come from
a) Can be produced by hybridomas derived from a fusion between spleen B lymphocytes and myeloma B cells
b) They have two aspartyl residues in the active site, one of which is a general acid while the other is a general base
c) 12 immunoglobulin domains
d) Matrix metalloproteases
e) Comes from the hypervariable loops
a) What forms the antigen binding sites of antibodies
b) What induces a conformation change on binding to RAS
c) What contains α-helices that recognise specific DNA sequences
d) What is a monoclonal antibody that binds to the EGF receptor, EGFR
a) Formed from the variable domains of light and heavy chain
b) SOS
c) FOS-JUN
d) Cetuximab
