Protein 5 Flashcards

1
Q

–Positive acute phase: increased during

A

metabolic stress

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2
Q

–Negative acute phase: decreased during

A

metabolic stress

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3
Q

What is Acute phase response

A

inflammation that can occur with metabolic stress

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4
Q

What is metabolic stress

A

A hyper metabolic, catabolic state

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5
Q

When does metabolic stress occur

A

In response to injury/trauma, sepsis, and some diseases

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6
Q

Under metabolic stress what is produced by the immune cells

A

Cytokines

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7
Q

Cytokines lead to?

A

Increased levels of several hormones

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8
Q

What is a side effect of metabolic stress on blood glucose

A

Hyperglycemia

Because of insulin resistance

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9
Q

What are 4 negative acute phase proteins

A
  • Albumin
  • Prealbumin (transthyretin)
  • Retinol binding protein
  • Transferrin
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10
Q

Positive acute phase proteins

A

C-reactive protein (CRP)

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11
Q

Negative acute phase proteins are good indicators of

A

morbidity and mortality and recovery from acute illness

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12
Q

Are negative acute phase proteins a good indicator of nutrition status

A

No

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13
Q

Assessment of NAP proteins gives dietitians a means to identify the patients that are most lik e l y t o d e v e l o p

A

m a l n u t r i t i o n

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14
Q

Glutathione is important for

A

Maintaining antioxidant balance in cells

Free radical scavenger

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15
Q

What does glutathione consist of

A

Glutamate

Glycine

Cysteine

(Contains SH group)

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16
Q

Albumin half life

A

18-21 days

17
Q

Prealbumin half life

A

2-3 days

18
Q

Retinol binding protein half life

A

12 hours

19
Q

Transferrin half life

A

8-10 days

20
Q

Albumin function

A

Carrier of nutrients

Maitinence of blood pressure

21
Q

Prealbumin function

A

Transport thyroxine and retinol

22
Q

Transferrin function

A

Transports iron

23
Q

Retinol binding protein

A

Present as complex of several proteins/molecules

24
Q

Monitored blood Proteins can be divided into

A

positive acute phase and negative acute phase proteins