Intigration Of Metabolism Flashcards
Fat cannot be made into
Glucose
TCA cycle mainly provides precursors for what process
Gluconogenesis
During fed state what is happening
Storing glycogen
Making TAG
Making protein
Some gluconogenesis
(Storing everything)
During early fasting state what is happening
First place body takes from to maintain blood glucose is the glycogen stores
Cori cycle (lactate sent to liver for gluconogenesis)
Glycogenolysis and gluconogenesis upregulated
TAG lipolysis not active
During starvation state what is happening
Sparing of protein
Increase lipolysis
Producing ketone bodies
Upregulated gluconogenesis
During metabolic stress insulin is?
What does this mean?
insulin secretion is increased
which means no production of ketone bodies
What is the significance of no ketone production during metabolic stress
FA cannot be used for energy
So mainly protein is degraded
What is the priority of metabolic stress
wound repair and host defense at the expense of body tissues
Some AA can be synthesized into
Fat and carbs
What does pyruvate dehydrogenase do?
Convert pyruvate to Acetyl CoA (non-reversible)