Prostate Cancer Flashcards
T/F: Prostate cancer is aggressive if it develops in older men.
False. It is aggressive it develops in young men, less so in older men.
What are 2 screening tests used for prostate cancer?
DRE and PSA
When does the prevalence of prostate cancer increase?
After age 50
At what age does prostate cancer mainly occur?
85% occurs in men after age 65
Location of prostate cancer
peripheral, subcapsuler cancer.
T/F: Prostate cancer will cause the same compression on the urethra as noted in BPH.
False, d/t the peripheral development it will not cause the same compression on the urethra
Risks of Prostate cancer?
- age (cumulative exposure to carcinogens)
- diet & ethnicity
- Familial (1st and 2nd degree relatives)
- Androgens
What is the most common type of prostate cancer?
~98% are adenocarcinomas
T/F: Prostate cancer presents differently in different men.
True
Does the malignancy spread?
Yes, it is locally invasive but as it advances it spreads through extension and metastases
What are the 2 structures most commonly impacted by the spread through extension?
seminal vesicle and urinary bladder
Manifestations of prostate cancer?
- no urinary manifestations d/t the peripheral development
- appear after invasion or mets
- earlier manifestations: dysuria, hematuria
- lower back daub
- prostatitis
Diagnostics of prostate cancer?
- hx, px
- digital rectal exam
- prostate specific antigen
- PROPSA
- Kallikrien
- Transurethral ultrasound
- biopsy
First line therapy of prostate cancer?
Antiandrogen
MOA of Antiandrogen?
supports the hormones that are supporting the growth of the tumour
