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Pharmacology > Prostaglandins > Flashcards

Prostaglandins Flashcards

1
Q

PG Renal Function

A
  • low BP->release of PGE2 & PGI2
  • Decreased Na and Cl retention-> PGE2 & PGI2 release
  • PGE2 & PGI2 release-> renin release
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2
Q

PGE2 & PGI2 renal function

A
  • incr. renal blood flow, GFR, and prevent ischemia of renal tissue
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3
Q

PG- Gastric function

A

PGE2 & PGI2 decrease acid secretion, stimulate mucus & bicarb. Secretion, alter mucosal blood flow

(Basically protects GI)

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4
Q

PGE1 (analogues)

A
  • misoprostol
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5
Q

Misoprostol

A
  • PGE1 analogue
  • off label use
  • Indications: NSAID induced ulcers, abortion inducer, K9 atopic dermatitis
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6
Q

Alprostadil

A
  • synthetic PGE1
  • human med: maintain PDA in infants
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Pharmacology (20 decks)

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