Prophylaxis

Question 1

Risk Factors for Thromboembolism

Answer 1

greater than 40 yo, prev VTE, HF, Acute resp. failure, recent major sx, IBD, MI, nephrotic syndrome, ischemic stroke, hypercoag state, vascular injury/stasis

Question 2

Medications that Increase VTE Risk

Answer 2

Estrogen, megestrol, tamoxifen, raloxifene, general anesthesia use > 40 min

Question 3

Low Risk of VTE

Answer 3

early ambulation or compression

Question 4

Moderate Risk of VTE

Answer 4

Heparin 5000 units SQ q8-12h

Question 5

High Risk of VTE

Answer 5

IPC and heparin 5000 units SQ q8h, LMWH, or fondaparinux (C/I in renal)

Question 6

GI Stress Risk Factors

Answer 6

Mech vent for more than 48 h, coagulopathy, septic shock, head or spinal cord injury, major traum/sx, burns greater than 30% BSA, renal/liver failure, high-dose CSS

Question 7

Enoxaparin PPX Dose

Answer 7

Dose: 40 mg daily or 30 mg q12h: CrCl less than 30: 30 mg daily

Question 8

Famotidine Dose

Answer 8

Dose: 20 mg q12h, or 40 mg daily; CrCl less than 50: half daily dose

Question 9

Pantoprazole Dose

Answer 9

40 mg daily or 12 hr