Neuromuscular Blockers Flashcards

1
Q

NMB Indications

A

Facilitate endotracheal intubation, mechanical ventilation, ctrl inc ICP, spasm assoc. w/ tetanus; sedation and analgesia optimized prior

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2
Q

Succinylcholine Dose

A

Indication: endotracheal intubation; Dose: 1-1.5 mg/kg up to 150 mg total dose

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3
Q

Succinylcholine Contraindications

A

personal/family h/o malignant hyperthermia, severe burns, myopathies w/ elevated creatine phosphokinase, penetrating eye injuries, pre-existing hyperkalemia

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4
Q

Cisatracurium

A

Indication: continuous blockade, 0.15-0.2 mg/kg bolus followed by 3 mcg/kg/min, range: 0.5-5 mcg/kg/min

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5
Q

Clinical Factors that Increase NMB Effect

A

HypoK, HypoCa, HypoNa, HyperMg, acidosis, hypothermia, renal/hepatic failure, neuromuscular diseases

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6
Q

Medications that Increase NMB Effect

A

Anesthetics (fluranes), AGs, Clinda, Polymixin, Vanco, Class 1 AAD, B blockers, CCBS, Lim dantrolene

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7
Q

Clinical Factors that Decrease NMB Effect

A

Alkalosis, HyperCa, demyelinating lesions

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8
Q

Medications that Increase NMB Effect

A

Anticholinesterases, Ca, Carbamazepine, phenytoin, theophyline, caffeine

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