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BMS 1002 > Prop of Cardiac Muscle - lecture 1 - S Roe > Flashcards

Prop of Cardiac Muscle - lecture 1 - S Roe Flashcards

1
Q

Approx how many beats does the average heart do a day?

A

115,000

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2
Q

What is the average daily volume of blood pumped per day?

A

8,000L

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3
Q

What are the 5 properties needed for Cardiac muscle?

A

Reliability Efficiency & Economy Redundancy Automatic and Co-ordinated Controllable depending on demand.

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4
Q

What is the name of the cell in the heart muscle?

A

Cardiac Myocyte - the develop from myoblasts. Held together by intercalated disks.

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5
Q

Why is the cardiac muscle cell branched?

A

To allow for it to pull in from many different directions.

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6
Q

The heart is said to work functionally as a Syncitium. What does this mean?

A

That the heart should work as if its only one cell. If you do something to one cell it happens to them all.

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7
Q

How are intercalated disks held together?

A

Tough tight junctions (to withstand pressure) Gap junctions to allow the passage of ions for electrical stimuli.

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8
Q

What is pacemaker tissue?

A

This is the conducting tissue i.e. SA Node, AV Node, Bundle of his and punki fibers

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9
Q

What ions move to create a action potential in pacemaker and non-pacemaker tissue?

A

NA, K, Cl

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10
Q

What is the resting potenital for non pacemaker tissue?

A

-92 mV RMP

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11
Q

What can you tell from the 2 peaks of the cardiac potential of a pacemaker tissue.

A

It tell us that it is autonomic

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12
Q

What happens at phase 0 of Non-pacemaker tissue?

A

Na+ channels open

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13
Q

Whay happens in phase 1 of non-pacemaker tissue?

A

Na+ channels closee and K+ and Cl+ channels open

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14
Q

What happens in phase 2 of Non-pacemaker tissue?

A

Slow prolonged opening of Cl+ channels

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15
Q

what happens in phase 0 of pacemaker tissue?

A

Long lasting Ca+ channels open and open at -40mv

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16
Q

What happens in phase 3 non pacemaker tissue?

A

There are 2 K+ channels (Ikr & Iks). The first 1 Ikr this allows potassium to leak in holding the plataeu and then the other channels open reversing this and letting K+ flood out of the cell making it more negative.

17
Q

What is phase 4 in Non-pacemaker tissue?

A

Resting membrane potential

18
Q

What phases are missing in Pacemaker cells?

A

1 & 2

19
Q

What happens in phase 3 of pacemaker cells?

A

Potassium comes back in

20
Q

Where does the Basal Caloric get its energy?

A

60% fats

35% oxidation of Carbs

5% oxidation of amino acids & ketone bodies

21
Q
A

BMS 1002 (4 decks)

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