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Endocrino > Prolactinoma > Flashcards

Prolactinoma Flashcards

1
Q

Niveles normales de PRL

A

<25 mujeres

<20 hombres

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2
Q

Principal causa de hiperprolactinemia

A

Fisiológica: embarazo
Fármacos: antagonistas dopaminergicos (metoclopramida, ISRs antidepresivos triciclicos,
Patológica:prolactinoma

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3
Q

Mecanismo de producción de leche en embarazo/galactorrea

A

Disminución de dopamina

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4
Q

Tratamiento para galactorrea

A

Cabergolina

Bromocriptina

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5
Q

Niveles de PRL y probable dx

A

50-100=probable tumor
100-200=50%
>200= tumor

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6
Q

Tipo de prolactinoma más común

A

Microadenoma

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7
Q

Características microadenoma

A

<1 cm

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8
Q

Causas de hiperprolactinemia de origen metabólico

A

Hipotiroidismo primario
Síndrome Stein Leventnal
ERC

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9
Q

Cómo se encuentran las hormonas sexuales en la hiperprolactinemia

A

Hipogonadismo hipogonadotropico

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10
Q

En los infantes cómo se manifiesta la hiperprolactinemia

A

Retraso púberal
Niñas:amenorrea, galactorrea
Niños: hábito eunocoide, testiculos pequeños y blandos

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11
Q

Manifestaciones de hiperprolactinemia en px premenopausicas

A

Niveles PRL
31-50=fase ultra corta, disminuye libido e infertilidad
51-75=oligomenorrea
>100=galactorrea, hipogonadismo, amenorrea

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12
Q

Manifestaciones de hiperprolactinemia en varones

A

Hipogonadismo hipogonadotrofico, disminuye libido, impotencia, infertilidad, ginecomastia, galactorrea
Tardía: osteoporosis

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13
Q

Tamaño macroadenoma

A

> 1cm

>10mm

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14
Q

Niveles de PRL en macroadenoma

A

> 100ng/ml

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15
Q

Manifestaciones clínicas macroadenoma

A

Cefalea, convulsiones, disminución visual, hemianopsia bitemporal*

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16
Q

Diagnóstico de hiperprolactinemia

A

1 toma de PRL alterada

17
Q

Gold de imagen en hiperprolactinemia

A

Rmn con gadolinio

18
Q

Oro en macroadenoma

A

Cromatografia de filtración en gel

Prueba de Polietilenglicol

19
Q

Indicaciones para cx tranesfenoidal

A

Craneo hipertensivo, compresión de nervios craneales III, IV, VI, panhipopituitarismo

20
Q

Indicación para radioterapia

A

Macroadenoma que no deja de crecer

21
Q

Indicaciones para referencia

A 
PRL >100
Hipogonadismo 
Galactorrea
Adenoma hipofisiario
Datos de compresión

Endocrino (7 decks)

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