Prolactinoma Flashcards
1
Q
What is a prolactinoma?
A
Pituitary adenoma (benign)
2
Q
What is the most common type of pituitary adenomas?
A
Prolactinoma
3
Q
What does it produce xs of?
A
Prolactin
4
Q
What is the local effect of it?
A
Headache VF defect CSF leak (rare)
5
Q
What type of VF defect may be present?
A
Bitemporal hemianopia
6
Q
What are the sx due to?
A
Effects of increased prolactin
7
Q
Name 4 sx
A
Female:
- Amenorrhoea
- Infertility
- Osteoporosis
- Galactorrhoea
Male:
- Low libido
- Low testosterone
- Impotence
- Galactorrhoea
8
Q
What Ix would you do?
A
Serum prolactin levels
MRI - dx
9
Q
What do you need to be aware of when measuring serum prolactin levels?
A
Pts taking anti-dopaminergic drugs as will have high prolactin
SO take careful hx
10
Q
How is it mx?
A
Dopamine agonist
- Cabergoline, Bromocriptine
11
Q
When do you do surgery?
A
Pts who can’t tolerate/ respond to medical Rx
12
Q
Which surgery is performed, if indicated?
A
Trans-sphenoidal surgery
