Progressive multifocal leukoencephalopathy

Question 1

What causes Progressive multifocal leukoencephalopathy?

Answer 1

JC polyoma virus

Question 2

In which type of patients does Progressive multifocal leukoencephalopathy typically present?

Answer 2

Immunocompromised patients

This includes AIDS patients with CD4 count <100, patients undergoing chemoradiotherapy, and those on immunosuppressant drugs.

Question 3

How does Progressive multifocal leukoencephalopathy manifest in patients?

Answer 3

Neurodegeneration over weeks to months

Symptoms may include cognitive decline, motor deficits, and other neurological issues.

Question 4

Key phrasing for Progressive multifocal leukoencephalopathy?

Answer 4

‘reactivation of latent infection’

Question 5

True or False: Progressive multifocal leukoencephalopathy is caused by an acute infection in immunocompromised patients.

Answer 5

False

The condition is due to the reactivation of a latent infection, not an acute infection.