Polio

Question 1

What type of virus causes polio?

Answer 1

RNA virus

Question 2

What part of the body does the polio virus infect?

Answer 2

Anterior horns of the spinal cord

Question 3

What is a classic symptom of polio?

Answer 3

Degeneration of motor neurons in one leg

Question 4

What is the result of motor neuron degeneration in polio?

Answer 4

One leg much smaller than the other leg

Question 5

What is the Salk vaccine?

Answer 5

Killed intramuscular vaccine

Question 6

What is the Sabin vaccine?

Answer 6

Live-attenuated oral vaccine

Question 7

What common feature accounts for the efficacy of polio vaccines?

Answer 7

Neutralizing antibodies in the circulation

Question 8

Which vaccine generates a CD8+ T-cell response?

Answer 8

Live-attenuated vaccine (Sabin)

Question 9

Which vaccine is capable of IgA secretion in the gut?

Answer 9

Live-attenuated vaccine (Sabin)

Question 10

What type of antibodies do both killed and oral polio vaccines generate?

Answer 10

IgG antibodies in the circulation