Progressive Meurological Disorders Flashcards
Multiple Sclerosis cause:
myelin sheath detoriates. disorder of CNS (eyes, brain, spinal cord). Can live normal life expectancy.
Nodes of Ranvier:
conduction velocity is accelerated.
MS is what?:
chronic, progressive disease of the CNS. Damaged areas form plaques (scar) which impede impulse transmission.
MS will cause:
Sensory motor and cognitive deficits.
MS Sensory symptoms:
Numbness, tingling, paresthesia, dizziness
MS motor symptoms:
weakness in limbs, tremor, fatigue, double vision, spasticity
MS cognitive symptoms:
difficulty concentrating, short term memory loss, personality change
Relapsing Remitting MS (RRMS):
attacks, flare ups. Attack from few hours to few days. Recover between attacks. MOST COMMON. eventually gets worse and worse.
Primary progressive MS (PPMS):
slow accumulation without remissions. men/ women equal.
Secondary progressive MS (SPMS):
remissions become less apparent and disease worsens over time.
Progressive Relapsing MS (PRMS):
steadily declining disease from beginning. LEAST COMMON.
Angioplatsy
helps relapsing remitting.
Pakrinsons is caused by:
basal ganglia (muscle tone/ posture) is affected. no longer releases dopamine.
basal ganglia (4):
the caudate nucleus, the putamen, the subthalamic nuclei, and the substantia nigra
PD motor symptoms:
pin rolling tremors, cogwheel rigidity, “mask-like” face (no expression), festinating gait.
