Principles of Surgical Oncology Flashcards
What characteristic links all cancers?
Uncontrolled cell growth and proliferation
True or False:
Cancer is considered a genetic disease.
TRUE
What are other factors that could cause cancer?
Chemical: environment, tobacco, pesticides
Physical: sunlight, trauma, chronic inflammation, implants, magnets
Hormonal: estrogen/progesterone, testosterone
Viral: papillomavirus, retrovirus, FELV/FIV
What do you call the length of time from date of diagnosis or start of treatment that 1/2 of the patients with the disease are still alive?
Median survival time
What do you call the period from diagnosis until the 1st recurrance?
Disease free interval
What do you call obtaining tumor tissue for microscopic analysis?
Biopsy
What do you call the process of determining the extent of a tumor and the presence of regional and distant metastasis?
Staging
What 3 tests does staging ALWAYS include?
CBC/Chem/UA
Thoracic radiographs
Regional lymph node aspirates/biopsies
In the World Health Organization TNM Classification system, what do T, N, and M stand for?
T = tumor
N = node
M = metastasis
True or False:
Metastasis can be present despite a lack of lymph node enlargement.
TRUE
In evaluating the lymph nodes, what needs to be done at minimum?
Fine needle spirate
What is the ultimate diagnostic tool in oncology?
Histopathology
What 2 pieces of information can histopathology tell you?
Tumor type
Tumor grade
What is the guideline for formalin fixation?
1 part tissue to 10 parts formalin
Always change ____ and instruments when performing biopsy on multiple tumors.
Gloves
For which types of lesions can a punch biopsy be used?
Superficial lesions - skin, oral, perianal tumors, liver
Which biopsy technique is best for ulcerated and necrotic lesions?
Wedge biopsy
When can you use an excisional biopsy?
Small cutaneous mass reexcision with 2-3 cm margin in all directions
Cytology clearly indicates a benign lesion
Tumor type does not change treatment plan
Risk of biopsy equal or higher to surgical risk
Surgical emergencies