Principles of muscular system Flashcards

1
Q

What are muscle cells specialized for?

A

Muscle cells are specialized for generating motile forces through the interaction of proteins, specifically actin and myosin.

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2
Q

What are the components of muscle structure?

A

Epimysium: Surrounds the entire muscle.
Perimysium: Surrounds muscle bundles.
Endomysium: Surrounds muscle fibers.
Muscle Fascicle: Bundle of muscle fibers.

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3
Q

What are the components of muscle cell structure?

A

Cell Membrane: Surrounds each cell, composed of a lipid bilayer.
Cytoplasm: Internal fluid of the cell, containing various organelles.
Endoplasmic Reticulum: Series of sacs involved in protein and lipid synthesis and transport.

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4
Q

What are the muscle-specific terms for cell membrane, cell cytoplasm, endoplasmic reticulum, and functional contractile unit?

A

Cell membrane: Sarcolemma
Cell cytoplasm: Sarcoplasm
Endoplasmic reticulum: Sarcoplasmic reticulum
Functional contractile unit: Sarcomere

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5
Q

What are the three types of muscle?

A

Skeletal muscle
Cardiac muscle
Smooth muscle

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6
Q

What are the characteristics of skeletal muscle?

A

Parallel bundles with stripes
Majority of muscle in the body
Capable of powerful contractions
Force is proportional to cross-sectional area
Moves bones and provides support for posture
Innervated by somatic and branchial motor nerves
Each skeletal muscle cell forms from fusion of myoblasts
Mature cells are multinucleated with peripheral nuclei

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7
Q

What are the characteristics of cardiac muscle?

A

Striped muscle similar to skeletal muscle
Found in the heart wall (myocardium) and great vessel walls
Branching network of cells linked electrically and mechanically
Contractions are less powerful than skeletal muscle but resistant to fatigue
Innervated by visceral motor nerves (parasympathetic and sympathetic)
Central nucleus, shorter cells than skeletal muscle
Fibers arranged in whorls and spirals
Contains specialized conducting system called Purkinje fibers

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8
Q

What are the characteristics of smooth muscle?

A

Smooth muscle has no stripes.
It consists of elongated spindle-shaped fibers.
Capable of slow and sustained contractions.
Found in various locations, including blood vessel walls, hair follicles, eyeball, and viscera.
Innervated by autonomic secretomotor nerves.

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9
Q

What are the types of muscle based on control, appearance, and association?

A

Skeletal muscle: Voluntary control, striated appearance, associated with the body wall (somatic).
Cardiac muscle: Involuntary control, striated appearance, associated with the heart (visceral).
Smooth muscle: Involuntary control, smooth appearance, associated with organs and blood vessels (visceral).

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10
Q

What is the origin attachment in skeletal muscle?

A

The origin is the proximal attachment, usually the stationary end.

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11
Q

What is the insertion attachment in skeletal muscle?

A

The insertion is the distal attachment, usually the mobile end.

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12
Q

What are the types of attachments in skeletal muscle?

A

There are three types of attachments: anatomically distinct tendons, broad areas of anchorage to a bony surface, and broad areas of anchorage to sheets of fibrocollagenous support tissue (fascia) which run between muscles.

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13
Q

What is the structure of tendons?

A

Tendons are cylindrical structures composed of tightly packed longitudinally running collagen fibers.

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14
Q

What is the largest tendon in the body?

A

The largest tendon in the body is the Achilles tendon, which connects the calf muscles to the calcaneum (heel bone).

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15
Q

What is the role of fibrocytes in tendons?

A

Fibrocytes in tendons have elongated flattened muscle nuclei and are relatively inactive.

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16
Q

What is the function of a tendon sheath?

A

The tendon sheath protects tendons from repeated friction as they traverse over bony surfaces.

17
Q

Which tendons commonly have tendon sheaths?

A

Long flexor tendons to the fingers commonly have tendon sheaths.

18
Q

What type of nerves innervate skeletal muscles?

A

Somatic motor nerves innervate skeletal muscles.

19
Q

How do muscles that have the same action on a joint tend to be innervated?

A

Muscles that have the same action on a joint tend to be innervated by the same nerve.

20
Q

Where does the motor nerve act on the muscle?

A

The motor nerve acts at the motor endplate, also known as the neuromuscular junction.

21
Q

What are neuromuscular junctions?

A

Neuromuscular junctions are specialized intercellular connections between a neuron and a skeletal muscle cell.

22
Q

What happens when a neuromuscular junction is stimulated?

A

Stimulation of a neuromuscular junction causes the myocyte (muscle cell) to contract.

23
Q

What neurotransmitter is released at the neuromuscular junction?

A

Acetylcholine (ACh) is released at the neuromuscular junction.

24
Q

What happens when acetylcholine is released at the neuromuscular junction?

A

Acetylcholine opens sodium channels, which elicits an action potential in the muscle cell and causes muscle contraction.

25
Q

Name these muscle morphologies

A
26
Q

What is the function of an agonist muscle?

A

The agonist muscle is the prime mover responsible for producing a specific movement.

27
Q

What is the function of an antagonist muscle?

A

The antagonist muscle opposes the action of the agonist muscle and helps regulate the movement.

28
Q

What is the function of a synergist muscle?

A

The synergist muscle assists the agonist muscle in producing a movement or helps stabilize the joint.

29
Q

What is the function of a fixator muscle?

A

The fixator muscle prevents unwanted movement at a joint by stabilizing the bone or joint involved.

30
Q

What happens when a muscle contracts isometrically?

A

Isometric contraction increases muscle tone but does not produce movement.

31
Q

What is the function of a flexor muscle?

A

A flexor muscle bends or decreases the angle at a joint.

32
Q

What is the function of an extensor muscle?

A

An extensor muscle straightens or increases the angle at a joint.

33
Q

What is the function of an abductor muscle?

A

An abductor muscle moves a body part away from the midline of the body.

34
Q

What is the function of an adductor muscle?

A

An adductor muscle moves a body part toward the midline of the body.

35
Q

What is the function of a rotator muscle?

A

A rotator muscle rotates or turns a body part around its axis.

36
Q

What is the difference between hypertrophy and hyperplasia?

A

Hypertrophy refers to an increase in the size of existing muscle fibers, while hyperplasia refers to an increase in the number of muscle fibers.

37
Q

What is atrophy?

A

Atrophy refers to the decrease in size or wasting away of muscle tissue, often due to disuse or lack of exercise.

38
Q

How does repair and regeneration differ in cardiac muscle compared to skeletal muscle?

A

In cardiac muscle, there is no resident stem cell population, so damage to cardiac muscle leads to the formation of collagenous scar tissue. In skeletal muscle, there are satellite cells that can divide and differentiate to form new muscle cells after tissue damage.

39
Q

What are satellite cells?

A

Satellite cells are myogenic cells located between the sarcolemma (cell membrane) and basement membrane of muscle fibers in skeletal muscle. They have the ability to divide and regenerate muscle tissue after injury.