principles of embryology Flashcards

1
Q

What is the pre-embryonic period of human development?

A

The pre-embryonic period begins at conception and lasts until the end of the second week of development. It includes processes such as fertilization, formation of the morula and blastocyst, and implantation of the blastocyst.

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2
Q

What is the embryonic period of human development?

A

The embryonic period spans from the end of the second week to the eighth week of development. During this time, germ layers develop, the placenta forms, and body systems start to develop from the trilaminar germ layers.

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3
Q

What is the foetal period of human development?

A

The foetal period begins at the eighth week of development and continues until birth (full term at 38 weeks). It is characterized by rapid growth and further development of visceral organs. The musculoskeletal system also becomes functional during this period.

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4
Q

What is the development of a morula?

A

After fertilization, the zygote undergoes mitotic divisions and splits into two cells, called blastomeres. The blastomeres continue to divide, resulting in a group of cells called a morula, which consists of around 16 cells.

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5
Q

What is the development of a blastocyst?

A

The morula undergoes further reorganization and forms a central cavity called the blastocyst cavity or blastocoel. At this stage, the structure is called a blastocyst. It consists of two main parts: the outer cell mass, known as the trophoblast, which contacts the endometrium for implantation and placenta formation, and the inner cell mass, known as the embryoblast, which is responsible for the development of the embryo itself.

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6
Q

What is the bilaminar disc?

A

During week 2 of development, the embryoblast divides into two layers: the epiblast and hypoblast, forming a two-layered structure called the bilaminar disc.

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7
Q

What are the two layers of the bilaminar disc?

A

The bilaminar disc consists of two layers: the upper layer called the epiblast and the lower layer called the hypoblast.

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8
Q

What forms within the epiblast of the bilaminar disc?

A

The amniotic cavity forms within the epiblast layer of the bilaminar disc.

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9
Q

What is gastrulation?

A

Gastrulation is the process during embryonic development where the two cell layers of the bilaminar disc (epiblast and hypoblast) transform into three germ cell layers: endoderm, mesoderm, and ectoderm.

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10
Q

What is the primitive streak?

A

The primitive streak is a groove that appears in the midline of the epiblast during the third week of development. It plays a crucial role in orchestrating gastrulation.

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11
Q

What are the three germ cell layers formed during gastrulation?

A

Endoderm: Formed by epiblast cells that migrate through the primitive pit and displace the hypoblast cells.
Mesoderm: Formed by epiblast cells that migrate through the primitive pit and lie between the epiblast layer and the newly created endoderm.
Ectoderm: Formed by the epiblast cells that remain in position.

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12
Q

What happens to the neural plate during embryonic development?

A

The lateral edges of the neural plate rise to form neural folds.

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13
Q

What is the result of the neural folds coming together?

A

The neural folds move towards each other and meet in the midline, forming the neural tube.

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14
Q

What is the role of the mesoderm in neuralation?

A

The mesoderm differentiates into the notochord, which stimulates neuralation.

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15
Q

What does neuralation cause in the ectoderm?

A

Neuralation causes the ectoderm to thicken.

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16
Q

What structures are formed from the thickened ectoderm during neuralation?

A

The thickened ectoderm forms the central and peripheral nervous systems.

17
Q

What are the three differentiations of the mesoderm?

A

The mesoderm differentiates into the paraxial mesoderm, intermediate mesoderm, and lateral plate mesoderm.

18
Q

What structures are formed from the paraxial mesoderm?

A

The paraxial mesoderm forms the dermatome (dermis layer of skin), myotome (muscles), and sclerotome (bones and cartilage).

19
Q

What does the intermediate mesoderm give rise to?

A

The intermediate mesoderm gives rise to urogenital organs, adrenal cortex, and reproductive organs.

20
Q

What structures are formed from the lateral plate mesoderm?

A

The lateral plate mesoderm forms the parietal mesoderm (parietal pleura and soft tissues of arms and legs), visceral mesoderm (visceral pleura, muscle walls of gut, heart, and circulatory system), and intraembryonic coelom (thoracic and abdominal cavities).

21
Q

What structures are derived from the endoderm?

A

The endoderm gives rise to the epithelial lining of the digestive and respiratory tracts, the lining of the urethra, bladder, and reproductive system, as well as the liver and pancreas.

22
Q

What is derived from the mesoderm?

A

The mesoderm gives rise to the notochord, musculoskeletal system, muscular layer of the stomach and intestine, and the circulatory system.