Principles of Medicine Flashcards

1
Q

How do you manage a S. Aureus infection?

A
  1. Stabilise patient
  2. Drain pus
  3. Administer antibiotics
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2
Q

What is impetigo?

A
  • Itching rash seen especially on the face

- Vesicles and pustules erupt and dry to form yellow-brown scabs

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3
Q

What is a characteristic histological finding for TB?

A

Granuloma with a core of necrosis

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4
Q

Which antibiotics are used to treat TB?

A
  • Rifampicin (bacteria)
  • Isoniazid (cell wall)
  • Pyrazinamide (granuloma)
  • Ethambutol (resistance)
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5
Q

What are the three strains of influenza that circulate in the human population?

A

H1N1
A H3N2
B

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6
Q

Which three drugs are used in triple therapy for HIV?

A
  • Tenofovir
  • Raltegravir
  • Atazanavir
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7
Q

What is the first non-invasive screening test for down syndrome?

A

Nuchal translucency ultrasound at 10-13 weeks

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8
Q

CVS is done between ____ weeks whereas amniocentesis is done between _____ weeks

A

11-12

15-19

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9
Q

When is the first ultrasound done in pregnancy?

A

8-10 weeks

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10
Q

When would pre-implantation genetic diagnosis be used?

A

When IVF is being used to conceive a child

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11
Q

What does the blood film for thalassemia look like?

A
  • Target cells

- Strangely shaped cells

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12
Q

What is the mutation in Kleinfelter syndrome?

A

47, XXY

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13
Q

What is the clinical presentation of Kleinfelter syndrome?

A
  • Appearance of normal male

- Infertility only incapacity

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14
Q

What is the mutation in Turner’s syndrome?

A

45, X

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15
Q

A young, male patient presents with:

  • Recurrent and spontaneous bleeds into joints, muscle and soft tissue
  • Bleeds are acutely painful

What could be the likely associated pathology?

A

Haemophilia

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16
Q

What is the distinguishing feature of Chronic Myeloid Leukaemia (CML) ?

A

Philadelphia chromosome in the bone marrow