Principles of Disease & Epidemiology and Disease Prevention Flashcards

1
Q

Define the following: Pathogen, Pathology, Etiology

A

Pathogen - Disease causing organism

Pathology - Scientific study of disease

Etiology - Causative agent of a disease

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2
Q

Define the following - Infection, Disease and Host

A

Infection: Invasion or colonization of the body by pathogenic organism.

Disease - Abnormal state in which all or part of the body is not functioning properly.

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3
Q

Define the following - Infection, Disease and Host

A

Infection: Invasion or colonization of the body by pathogenic organism.

Disease - Abnormal state in which all or part of the body is not functioning properly.

Host - Organism that shelters and supports the growth of pathogenic organisms.

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4
Q

Define Control

A

The reduction of disease incidence, prevalence, morbidity or mortality to a locally acceptable level as a result of deliberate efforts; continued intervention measures are required to maintain the reduction. (Eg. Diarrhoeal diseases)

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5
Q

Define elimination of disease

A

Reduction to zero of the incidence of a specified disease in a defined geographical area as a result of deliberate efforts; continued intervention measures are required to maintain the reduction. E.g. neonatal tetanus

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6
Q

Define elimination of infections

A

Reduction to zero of the incidence of infection caused by a specific agent in a defined geographical area as a result of deliberate efforts; continued measures to prevent re-establishment of transmission are required. E.g. measles, poliomyelitis

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7
Q

Define eradication and extinction

A

Eradication: Permanent reduction to zero of the worldwide incidence of infection caused by a specific agent as a result of deliberate efforts; intervention measures are no longer needed. E.g. smallpox

Extinction - The specific infectious agent no longer exists in nature or in the laboratory (no example).

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8
Q

What are normal flora?

A

Microbes that are on or in a host, but do not cause disease. They can be transient or resident.

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9
Q

Define microbial antagonism and symbiosis

A

Microbial antagonism - Belief that normal flora benefit a host by preventing overgrowth of more harmful microbes - in vagina, ear and on skin.

Symbiosis - Close relationship between two different organisms.

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10
Q

Lis

A
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11
Q

List and define the various types of relationships

A

Commensalism - One organism benefits, the other is unharmed.(harmless)

Mutualism - Both organisms benefit. (Helpful)

Parasitism - One organism benefits and other is harmed (harmful)

Opportunism - Organism don’t cause disease unless appropriate condition exists (potentially harmful).

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12
Q

Give the classification of diseases based on transmissibility

A

Communicable diseases - Transmitted directly or indirectly from one host to another.
* Contagious diseases - Easily spread from one person to another.

Non-communicable diseases - Not spread from one host to another.

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13
Q

Classify disease based on frequency of occurrence (S.E.E)

A

Sporadic - Occurring irregularly, haphazardly from time to time and generally infrequently.

Endemic - The constant presence of disease or infectious agent within a given geographical area or population group.

Epidemic - The occurrence in a community or region of cases of an illness, specific health related behavior clearly in excess of normal expectancy

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14
Q

Classify disease based on frequency of occurrence

A
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15
Q

Classify disease based on frequency of occurrence (S.E.E.P)

A

Sporadic - Occurring irregularly, haphazardly from time to time and generally infrequently.

Endemic - The constant presence of disease or infectious agent within a given geographical area or population group.

Epidemic - The occurrence in a community or region of cases of an illness, specific health related behavior clearly in excess of normal expectancy.

Pandemic - An epidemic occurring worldwide, or over a wide area, crossing international boundaries and usually affecting a large number of people.

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16
Q

Classify disease based on severity

A

Acute - Develops quickly/lasts short time

Chronic - Develops slowly/lasts long time

Subacute - In between acute and chronic

Latent - causative agent remains inactive for a period of time and then becomes active to produce symptoms.

17
Q

Delineate the extent of host involvement

A

Primary Infection - Acute infection caused by initial illness.

Secondary infection - Caused by opportunistic microbe after host immune system weakened by primary infection.

Subclinical infection - Does not noticeable disease.

18
Q

What are the stages of disease development?

A

1: Incubation period - no signs or symptoms
2: Prodromal period - mild signs or symptoms
3: Illness - Death can result if immune responses and/or medical treatments fail
4: Period of Decline
5: Period of Convalescence (mild to no symptoms.(Recuperation)

19
Q

What are the three routes of disease transmission

A

Contact: Direct, Indirect, Droplet

Vehicle - Non- living

Vectors

20
Q

What are the three main routes of disease transmission

A
  • Contact: Direct, Indirect, Droplet
  • Vehicle - Non living object that transmits disease causing pathogen.
  • Vectors -
21
Q

What routes do microbes use to exit host

A

Respiratory tract: Via cough/sneeze

GIT: Via faeces

Urogenital: Via vaginal/penile secretions

Skin: Via open wounds

Blood: Open wounds, Surgery, Syringes

21
Q

What are nosocomial infections and what proportion of patients acquire them?

A

Infection acquired during the course of stay in a hospital, nursing home, or other health care facility.

5-15% of patients

22
Q

What type of organisms are implicated in nosocomial infections

A

Gram negative opportunistic drug resistant bacteria often involved - Pseudomonas spp

23
Q

What are the three types of reservoirs for infection

A

Human, Animal and non-living

23
Q

How are the pathogens that cause nosocomial infections introduced into the human body and what group of people are susceptible to infection?

A

Introduced to body via surgery or catheter or

*Direct contact with other patients or staff

*Compromised hosts are most susceptible

24
Q

What routes do microbes use to exit host

A

Respiratory tract: Via cough/sneeze

GIT: Via faeces

Urogenital: Via vaginal/penile secretions

Skin: Via open wounds

Blood: Open wounds, Surgery, Syringes

25
Q

How do predisposing factors of disease work?

A

They make the body more susceptible to disease or alter the course of disease.

Examples: Age, Gender, Fatigue, Climate, Poor nutrition

26
Q

What routes do microbes use to exit host

A

Respiratory tract: Via cough/sneeze

GIT: Via faeces

Urogenital: Via vaginal/penile secretions

Skin: Via open wounds

Blood: Open wounds, Surgery, Syringes

26
Q

What are the three types of reservoirs for infection

A

Human, Animal and non-living

26
Q

How do predisposing factors of disease work?

A

They make the body more susceptible to disease or alter the course of disease.

Examples: Age, Gender, Fatigue, Climate, Poor nutrition

26
Q

What are the reasons for the new emerging diseases?

A

Use of antibiotics and pesticide
Climate changes
Travel
Lack of vaccinations
Improved case reporting