Principal Effector Functions Flashcards

1
Q

IgG subclasses

A

Stimulated by IFN-gamma via Th1

Functions: FcR dependent phagocyte responses; complement activation; neonatal immunity (placental transfer)

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2
Q

IgE

A

Stimulated by IL-4 from Th2 Functions: Immunity against Helminths, mast cell degranulation (immediate hypersensitivity)

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3
Q

IgA

A

Mucosal immunity (transport of IgA through epithelial)

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4
Q

IgM

A

Complement activation

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