Principal Effector Functions Flashcards
1
Q
IgG subclasses
A
Stimulated by IFN-gamma via Th1
Functions: FcR dependent phagocyte responses; complement activation; neonatal immunity (placental transfer)
2
Q
IgE
A
Stimulated by IL-4 from Th2 Functions: Immunity against Helminths, mast cell degranulation (immediate hypersensitivity)
3
Q
IgA
A
Mucosal immunity (transport of IgA through epithelial)
4
Q
IgM
A
Complement activation