Major Cytokine And Chemokine Families Flashcards
1
Q
Tumor Necrosis Factor; Example and Role
A
Ex: TNF-alpha; Role in inflammation
2
Q
Interleukins & Interferons; Example and Roles
A
Ex: IL-2-T cell growth and division, IFN-alpha-Defense against viruses, IFN-gamma- cell-mediated immunity
3
Q
Chemokines-example and role
A
Ex: IL-8; Role- Chemotaxis to site of inflammation; Chemotaxis of cells to 2ndary lymphoid organs
4
Q
Transforming Growth Factor Beta; Example and Roles
A
Ex: TGF-beta; Role-: Down-regulation of immune response; Regulation of embryonic development
5
Q
Growth Factors; Colony Stimulating Factors; Example and Roles
A
Ex: EGF-wound healing; synthesis of ECM
GM-CSF-stimulation of Hematopoiesis
6
Q
Interleukin-1; example and role?
A
Ex: IL-1; role in inflammation
