Primary vs Secondary Response Flashcards
1
Q
When does primary response occur?
A
On initial contact with new foreign antigen
2
Q
What antibodies are released during primary response?
A
- IgM is first molecule released
- This disappears after 10 days
- As IgM decreases, there is concurrent rise in IgG
3
Q
When does secondary response occur?
A
If the same antigen is encountered again
4
Q
What is 2ary response like in comparison to 1ary?
A
Rapid and greater rise in IgG molecules specific to that antigen
Very limited rise in IgM
5
Q
Why is the 2ary response much faster and greater?
A
Memory B cells for this antigen remain in blood - express specific B cell receptors on their surface
These receptors are the antibodies that the B cells will produce when they have been activated
6
Q
What is 2ary response mediated by?
A
Long-lived memory T cells and memory B cells (immunological memory)
