Primary metabolites 1 Flashcards

1
Q

what makes up a fatty acid a

A

hydrocarbon chain

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2
Q

what is special about the number of carbons that makes up the chain

A

there is usually an even number of carbons

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3
Q

what does the fatty acid chain start and end with

A

starts with a methyl end, omega,n

ends with a carboxyl end, delta, COOH

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4
Q

what does saturated/unsaturated mean

A

is there is a single bond its saturated

unsaturated = double bond - longer word - double

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5
Q

what is a fatty acid called if there are several double bonds

A

polyunsaterated

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6
Q

what does 18:3,n-3 mean

A

18 carbons: 3 double bonds (desaturations)

, n-3 position of the first double bond defined from the methyl end, n

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7
Q

what is the shorthand if the fatty acid is saturated with 18 carbons

A

18:0, X

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8
Q

what is FAS and what does it do

A

Fatty Acid Synthase, multi enzyme system in the cytosol, that catalyses fatty acid synthesis, a system

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9
Q

what does elongase do

A

extends the fatty acid in 2 carbon units

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10
Q

what do desaturases do, and what end is this worked out from

A

add double bonds to a fatty acid, the carboxyl COOH end

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11
Q

major function of fatty acids

A

components of phospholipids - cell membranes

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12
Q

what is a trigycaride

A

glycerol + 3 fatty acids
- fatts and oils - type of fat
important carbon storage molecule - more space efficient than carbs - they don’t hold water

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13
Q

what is the molecule that FAS predominantly produces - the max length molecule

A

palmitic acid - 16 carbons long

most common saturated FA in humans

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14
Q

what are essential fatty acids

A

we can’t make them - need to get them from our diets

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15
Q

what important molecule do we need to make from essential amino acids, what are they and what do they do

A

eicosanoids - short range hormones - for inflammation and nerve function

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16
Q

what are trans fatty acids

A

made unnaturally, as a result of the hydrogenation process - double bond formed - don’t have a kink in chain - less fluidity - not good eg, oils/butter

17
Q

what is different about an unsaturated fatty acids chain and why is this bad

A

unsaturated fats - double bonds - have a straight chain - no kinks - this means there is less fluidity

18
Q

what is the name of the fungus that produces many fatty acids, and what specifically does it produce

A

Mortierella alpina

immediate precursor for eicosanoids

19
Q

what does EL and the delta sign (small triangle) stand for

A

elongase

desaturase

20
Q

what type of enzymes do we lack and so what FAs can’t we produce

A

we lack some deltas (desaturases)
Can’t make n6 or n3 fatty acids
precursors for eicosanoids

21
Q

what is the minimum requirement FA we need in our diets

A

need FA linoleic acid - (18:2) in the n6 family

18:3 in the n3 family