Primary lymphoid tissues: bone marrow Flashcards

1
Q

What are primary lymphoid tissues?

A

Tissues where lymphocytes develop and mature to a stage where they are able to recognise antigen.

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2
Q

What are primary lymphoid tissues also known as?

A

Central lymphoid organs

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3
Q

What are all immune cells derived from? What else is derived from this?

A

Haematopoeitic stem cells in the bone marrow.

Its also the site of origin of red blood cells and platelets.

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4
Q

What are the two types of marrow?

A

red and yellow

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5
Q

What are the two types of bone marrow involved with?

A

Red marrow is involved in haematopoiesis. Yellow marrow is made of adipocytes (fat cells).

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6
Q

What do lymphocytes descend from?

A

A common lymphoid progenitor.

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7
Q

Where do B cells mature?

A

They mature entirely in the bone marrow and enter the blood, most die within a few days as they fail to meet their antigen.

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8
Q

What is the T cell life cycle like?

A

T- cells leave the bone marrow as immature progenitors and travel to the thymus, via the blood, to complete maturation and undergo selection.

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