Lymphocytes and mast cells Flashcards
What happens to B cells once they’re activated?
They differentiate into antibody secreting plasma cells as part of the specific immune response.
What are T cells and what are the two types?
Thymus-matured lymphocytes.
Cytotoxic T lymphocyte (CTL) which kills virally infected cells.
Helper T-lymphocytes which activate other cells such as B cells and macrophages.
What are natural killer (NK) cells?
Large, granular lymphocytes which form part of the innate immune response. Although they lack antigen specific receptors they can detect and attack some virally infected cells.
Where are mast cells found?
Many tissues, mainly near small blood vessels.
What happens when mast cells are activated?
They release substances from their granules which affect vascular permeability. The granules contain histamine and heparin.
What are mast cells known for?
Their role in allergy, they’re also thought to play a role in protecting the mucosal surfaces from pathogens.
