Preventive Flashcards
Parents refuse to immunize children….what to do?
- Inquire about concerns, address non-confrontationally, give written materials
- Ask them to think about it and discuss at next visit
- Tell them to always notify medical people of kids underimmunized status during ill visits, especially to ED
- Have sign refusal form that lists risks of not vaccinating child (must sign at every well-child visit…this can be persuasive)
When is DTaP given?
2, 4, 6, 15-18 months, and kindergarten visit
4th dose can be given as early as 12 months old, as long as 6 months elapsed since 3rd dose given
Most effective way to prevent drowning?
Fence around the pool
What type of DTaP vaccine was given in the olden days that was effective in preventing disease, but had higher rates of local and systemic reactions?
Whole cell pertussis vaccines (DTP)
What is the current pertussis vaccine used in U.S.?
Acellular (DTaP)
What’s the difference between Tdap and DTaP?
Less pertussis antigen (little p) and less diphtheria antigen (little d)
What age do you no longer use DTaP?
7 and older (too much p)
Between what age should patients get a single dose of Tdap?
Adolescents 11-18 (preferably between 11-12)
*This replaces the Td booster that was previously given (commercial names for licensed vaccines are Boostrix and Adacel- 2 brands can be used interchangeably)
Which 3 vaccines can be given to adolescents at the same visit?
Tdap, meningococcal, and HPV
Do you adjust the immunization schedule for prematurity?
No, immunizations are based on postnatal age, even for preemies
What is the difference between Td and DT?
Td vaccine is booster similar to Tdap
DT vaccine is a variant of DTaP given to small children who can’t handle aP component
Little d is less amount of diphtheria toxoid
In kids 7-18 what is substituted for a single dose of Td in the catch up series?
Tdap
If you substitute Tdap for a single dose of Td in the catch up series for kids 7-18, does it count as the Tdap booster?
Yes, another one isn’t needed at 11
What should be the booster for kids 10-18 with regard to tetanus, diphtheria, pertussis?
Tdap (you use Td for other doses)
If you give DTaP to a kid 7 or older (which you shouldn’t), does it count as the adolescent Tdap booster?
Yes
Who to give DTaP v. Tdap?
DTaP is “D” for diapers (no DTaP in kids 7+)
Tdap is “T” for teens
What are contraindications to tetanus, pertussis, diphtheria vaccines?
- Serious allergic reaction: Refer to allergist to confirm allergy and asses need for desensitization
- Encephalopathy within 7 days of receiving pertussis-containing vaccine (this isn’t a contraindication for Td though)
- No other identifiable causes for the reaction
What are some things that are misconstrued as contraindications or precautions for administering Tdap, but it is actually safe to administer the vaccine when indicated?
- History of extensive limb swelling (that wasn’t part of an arthus reaction) after getting vaccine
- Stable neurological conditions, including well controlled seizures and cerebral palsy
- Brachial neuritis
- Contact allergy to latex gloves
- Pregnancy/breast feeding
- Immunosuppression
- Minor illnesses including antibiotic use
Is pregnancy a contraindication for Tdap or Td?
No…don’t be fooled by pregnant teenager
What should close family contacts of newborns be immunized for if the immune status is lacking or unknown?
Pertussis
If an adolescent has a history of pertussis should they receive Tdap immunization?
Yes
Is tetanus immune globulin indicated for any clean wounds?
No
When does a child have to get a tetanus vaccine?
If the immunization status is unknown or if the child has received less than 3 tetanus vaccines
When is a booster indicated for tetanus?
If it’s been more than 10 years
What do you do for a kid with a dirty wound that has received less than 3 tetanus vaccines or history unknown?
Tetanus vaccine and TIG
For a dirty wound, when is a booster indicated?
If it has been more than 5 years since last tetanus given
If you have to give tetanus to a kid between 11-18, what should they get?
Single dose of Tdap (versus Td) if they haven’t gotten a previous Tdap
*If the adolescent got Tdap in the past or if Tdap isn’t available, give Td
If you need tetanus immune globulin, but it isn’t available, what do you give?
IV immune globulin
What constitutes a dirty wound?
Risk of contamination from feces, dirt, or saliva. Severe injuries like burns, frostbite, or crush injuries.
What has decreased the incidence of meningitis and epiglottitis?
Hib vaccine
When do you give Hib vaccine?
Depending on vaccine, either 2, 4, 6 months, or 2 and 4 months
What vaccine preventable disease can cause liver disease and hepatocellular carcinoma?
Hepatitis B
In how many cases of Hep B are no identifiable risk factors identified?
1/3
When is Hep B given?
First dose at birth (prior to d/c from nursery), second at 1-2 months, third at 6-18 months
If you are given a kid who hasn’t been completely immunized against Hep B, what do you do?
Begin or complete the 3 part series
What is the only absolute contraindication to Hep B vaccination?
Severe allergic reaction to a prior dose
Is pregnancy or autoimmune disease (like SLE) a contraindication to Hep B vaccine?
No
When do you give a newborn Hep B immunoglobulin in the first 12 hours of life in addition to the routine immunization?
If mom has hepatitis B (HBsAg positive) or mom has an unknown hepatitis status
When should an infant born to a HBsAg positive mom have their post vaccination status verified and how?
9-12 months of age, serological testing (HBsAb)
What high risk groups should have serologic testing done to confirm immunity after the Hep B vaccine series?
Immunocompromised patients, hemodialysis patients, high risk jobs (health care, prostitute)
What 3 “turning points” are children at risk for Hepatitis B?
- Intrapartum
- Early childhood (household contacts or group care facilities)
- Adolescence (sexually transmitted and IV drug use)
What are the age restrictions for the combo DTaP/HepB/IPV vaccine?
- Can’t be used in kids 7 or older (only approved for primary series, not used for booster dose at kindergarten or later)
- Can’t be used before 6 weeks of age (can’t be used for the birth dose of Hep B)
When do preemies get their Hep B vaccine?
Within 30 days of life or before discharge (whichever is first)
*Even if they are less than 2kg
Does the birth vaccine of Hep B in infants under 2kg count towards the completion of the series?
No
What is given for post exposure prophylaxis for Hep B in infants and other unvaccinated patients?
HBIG and start Hep B series
What is given for post-exposure prophylaxis for hepatitis B in patients who have received the full vaccination series and are antibody positive?
Nothing
What is given for post-exposure prophylaxis for Hep B in patients who received the full vaccination series and are antibody negative?
HBIG and full revaccination…they are considered pretty much unvaccinated
What is given for post-exposure prophylaxis for Hep B in patients who have unknown immunization status?
Test for antibody, if negative, give HBIG and start series
When do kids in U.S. get Hepatitis A vaccine?
At 1
What are the trade names for hepatitis A vaccine?
Havrix and Vaqta
How is Hepatitis A given?
2 doses, at least 6 months apart, same brand (start at 1)
Is an immunocompromising condition a contraindication to receiving Hep A vaccine?
No
What are contraindications to Hep A vaccine?
Hypersensitivity or allergic reaction to vaccine components (aluminum hydroxide, phenoxyethanol)
If a kid under 1 is traveling to an area that is endemic for hepatitis A, what do you do?
Give passive immunization with immune globulin
For a kid older than 12 months traveling to an area endemic for Hepatitis A, what do you do?
Give hepatitis A vaccine 4 weeks prior to departure (2 at the very least)
What is the meningococcal vaccine given and what strains does it cover?
MCV4 vaccine (old vaccine was MPSV4, a polysaccharide model)
A, C, Y, W-135…provides improved, longer lasting immunity than old model and reduces carrier state
What subtype causes more than half of meningococcal disease in infants?
B (vaccine provides no protection for this)
“B is the Bad strain of meningococcus, most common in Babies”
When is routine immunization against meningococcemia with MCV4 vaccine indicated?
- Pre-adolescents at 11-12 visit
- At high school entry or 15 (whichever comes first), if not previously immunized
- Kids entering freshman college dorms (previously unvaccinated)
Is syncope after vaccination a contraindication to future vaccination?
No, syncope after vaccination is common, especially in adolescents and young adults
When can kids with HIV infection receive the MCV4 vaccine?
If they are over 2
What kids would be considered at increased risk for meningococcemia?
Terminal complement deficiency, asplenia (including functional), travel to prevalent area
When would you give MCV4 to a kid who already got MPSV4?
Still at risk and it has been 3 years since receipt of MPSV4
Gardasil and Menveo are trade names for what vaccine?
HPV
What is the recommended age for the HPV vaccine in girls?
11-12
How young can girls get HPV vaccine?
9
Is HPV vaccine recommended for males?
Yes, since HPV is an STD it provides protection against anal cancer along with vaginal warts
When is catch up HPV vaccination recommended for females?
Between 13-26 if not previously vaccinated
How is cervical cancer screening done in females who received the HPV vaccine?
According to recommended schedules (vaccine isn’t considered to be a substitute for routine cervical cancer screening)
Since intro of MMR vaccine, incidence of measles, mumps, and rubella has decreased by what %?
99%
When is MMR given?
Between 12-15 months of age, with booster at school entry
When is second dose of MMR given?
4-6 years
*Booster dose of MMR can be given at any visit as long as 4 weeks elapsed since first dose
Do MMR vaccines given before 12 months (for travel or during an outbreak) count towards completion of series?
No, two doses must be given at 12 months of age or later
7 month old infant exposed to measles…what to do?
Under 72 hours (3 days) from exposure: Measles vaccine (rule applies to infants who are at least 6 months)
Over 72 hours, but under 6 days from exposure: Measles immunoglobulin
How man doses of MMR would an infant between 7-11 months traveling to a part of the world where measles is endemic receive?
3…they would need to be immunized for travel (considered short term immunization) and then resume the regular immunization schedule for MMR at the appropriate age
When can you give MMR with other live vaccines?liv
MMR may not be given within 4 weeks of other live vaccines (varicella and live influenza)
*Live vaccines can be given together or in a combined vaccine
What do up to 15% of kids who receive MMR develop?
High fever (>103) that occurs within 12 days after vaccine administration and lasts 1-2 days
*5% will also develop a rash during this time frame
What to do for a kid who got MMR and then got a high fever and/or rash within 12 days that lasts 1-2 days?
Reassurance
What are the absolute contraindications to MMR?
- Severe allergic reaction to a vaccine component, neomycin, or gelatin
- Pregnancy in patient
- Severely immunocompromised (chemo, AIDS)
What 9 things are not contraindications for MMR?
- Positive TB skin test
- Concurrent TB skin testing
- Pregnancy in mother or other close contact
- Breast feeding
- Immunodeficiency in member of household
- Egg allergy
- Mild or a symptomatic HIV infection
- Non life threatening reaction to neomycin
- History of seizure (slightly increased risk, but not a contraindication)
Do you withhold the MMR vaccine for a mild reaction?
No
Can you place a PPD and give an MMR together?
A PPD can be placed with MMR with no mitigation of its effect
PPD shouldn’t be placed within 4-6 weeks after MMR has been given
Can MMR and varicella be given together?
Yes, they often are at the 12 or 15 month visit and at the kindergarten visit
Who is MMR contraindicated in?
Pregnant (do documented cases of birth defects from vaccines, but still contraindicated)
Is a therapeutic abortion indicated if MMR is accidentally given to a pregnant woman?
Not medically
What is the MMRV vaccine associated with?
Higher rates of febrile seizures in kids 12-23 months (not preferred over single vaccine components MMR and Varicella)
What kids is MMRV contraindicated in?
HIV
When is varicella vaccine given?
Between 12-15 months with booster upon entry to kindergarten (between 4-6)
Should you vaccinate an older kid who has not had chickenpox?
Yes