Preventing adhesions in laparoscopic surgery: the role of anti-adhesion agents TOG 2019 Flashcards
Classification of anti-adhesive measures
Types of physical barriers
How long should barrier agents work - ideally > 3 days during the peak mesothelial re-epithelialsation
How long does oxidised regenerated cellulose taken to absorb
2 weeks, applied to damaged peritoneum, forms gel
How is polytetrafluoroehtylene used (Gore-tex). Is it absrobable?
Non absorbable membrane, sutured onto peritoneal surfaces and requires 2nd operation for its removal.
What is the absorbtion time of chemically modified sodium hyaluronate-carboxymethylcellulose
Froms gel within 24-48 hours
Absorbed within 7 days
How does polyethylene glycol based liquid gel barrier work and how long for absorbtion
Sprayed onto target tissue, gelatinous barrier remains intact 5-7 days. Absorbed after 30 days
What solution is in ADEPT? How long does in take to be absorbed
Icodextrin solution - 4% alpha 1.4 glucose polymer solution
Slowly absorbed over 4 days
