Pretest with EKG! (and others) Flashcards
organophosphate compounds inhibit __________
acetylcholinesterase,
The treatment for organophosphate toxicity is
atropine and pralidoxime
Atropine-anticholinergic/ inhibits excess acetylcholine.
Pralidoxime- regenerates
acetylcholinesterase
Flumazenil reverses _________
benzodiazepines
GHB vs other sedative/hypnotic overdoses
vs other sedative/hypnotic overdoses, the level of consciousness fluctuates quickly
between agitation and depression.
γ-Hydroxybutyrate
The most useful diagnostic test/treatment in a suspected CO poisoning is
COHb level
mainstay of treatment is the delivery
of oxygen
Acetaminophen concentration must be measured ______ after ingestion and then plotted on the nomogram.
between 4 and 24 hours
_________ is notorious for causing sz refractory to standard therapy
INH
Pyridoxine (vitamin B6) is the treatment
Glyburide is a commonly prescribed __________
sulfonylurea
lasts 24 hours–> Hypoglycemia secondary to sulfonylureas generally requires
hospital admission to monitor for recurrent hypoglycemia
Aspirin overdose acid/ base
A mixed respiratory alkalosis and metabolic acidosis is typically seen in adults
Agents that do not adsorb to charcoal include
ions- lithium
hydrocarbons
metals
ethanol
________ should be used as the first-line
agent for nearly all cocaine toxicities.
Benzos
Opioid withdrawal presents with
mild tachycardia yawning rhinorrhea piloerection NVD diaphoresis myalgias/ arthralgias, anx
Toxic alcohol and serum osmolarity
- If ↑ low molecular weight molecules,
(acetone, toxic ETOH, mannitol)
–>
-↑ osmolarity (more than what is calculated from the regular serum molecules)
osm gap > 50 diagnostic of toxic etoh
acetaminophen od rx
NAC
glutathione precursor to reduce NAPQI (N-acetyl-p-benzoquinoneimine)– the
toxic metabolite of acetaminophen.
most effective within 8 hours of the ingestion, use up to 24
The finding of _________ is considered the hallmark of ethylene glycol ingestion
crystalluria