Prescribing in renal impairment Flashcards
1
Q
Colchicine in renal impairment
A
May be used with caution
The BNF advises to reduce the dose if eGFR is 10-50 ml/min and to avoid if eGFR < 10 ml/min
2
Q
Why are ACEi and ARBs nephrotoxic?
A
Reduce the GFR by vasodilating the efferent arteriole more than the afferent
3
Q
Why should metformin be stopped when IV contrast is given?
A
Risk of lactic acidosis (metformin will not be excreted due to nephrotoxic load of contrast)
4
Q
Which drugs of abuse have been implicated in rhabdo?
A
Cocaine
Heroin
Methadone
Metamphetamines
5
Q
Drugs to stop if renal impairment confirmed - DAMN
A
Diuretics
ACEi/ARBs
Metformin
NSAIDs
