Drug interactions Flashcards
1
Q
Gentamicin, vancomycin
A
nephrotoxicity
ototoxicity
2
Q
ACEi e.g. lisinopril, ramipril
A
low BP
electrolyte abnormalitiess
AKI
dry cough
3
Q
beta blocker e.g. bisoprolol
A
low BP
low HR
wheeze in asthmatics
worsens acute HF (but helps chronic HF)
4
Q
CCB e.g. diltaziem, verapamil
A
hypotension
low HR
peripheral oedema
flushing
5
Q
diuretics
A
hypotention
AKI
6
Q
digoxin
A
N/V/D
blurred vision
confusion and drowsiness
yellow green vision
7
Q
amiodarone
A
pulmonary fiboriss
thyroid disease
skin greying
8
Q
lithium
A
early: tremor
intermediate: tiredness
late: arrythmia, seizure, coma. renal failure, DI
9
Q
haloperidol
A
dyskinesias
10
Q
clozapine
A
agranulocytosis
11
Q
Steroid side effects
A
STEROID Stomach ulcer Thin skin Edema Right and Left HF Osteoporosis Infection Diabetes Syndrome of Cusshings
12
Q
NSAID
A
NSAID
No urine (renal failure) Systolic dysfunction (HF) Asthma Indigestion Dyscrasia
13
Q
Which antibiotic should never be prescribed with methotrexate?
A
Trimethoprim (also co-trimoxazole which contains trimethoprim)
