Prescribing

Question 1

Pharmacokinetics is how the drug works in the body. True/false?

Answer 1

True

Question 2

Pharmacodynamics is how the body works with the drug. True/false?

Answer 2

True

Question 3

Acidic drugs absorb in a basic environment and basic drugs absorb in an acidic environment. True/false?

Answer 3

False - acidic absorbs in acidic and basic absorbs in basic

Question 4

Do older patients have a greater acidic or basic environment?

Answer 4

Basic

Question 5

What basic plasma protein binds to acidic drugs?

Answer 5

Albumin

Question 6

What acidic plasma protein binds to basic drugs?

Answer 6

Alpha-1 acid glycoprotein

Question 7

Define the volume of distribution

Answer 7

The volume of drug given to a patient that is distributed within plasma alone

Question 8

Increased fat increases/decreases the volume of distribution of lipophilic drugs

Answer 8

Increases

Question 9

What is the biological half-life of a drug?

Answer 9

The time taken for the biological/pharmacological activity of the drug to reduce by half

Question 10

Define the therapeutic index

Answer 10

(50% lethal dose) / (50% effective dose)

Question 11

What drugs should be given prophylactically with opioids? Why?

Answer 11

Lactulose/senna

Constipation

Question 12

Which NSAIDs should be prescribed in older people?

Answer 12

Naproxen/ibuprofen