Polypharmacy Flashcards
1
Q
What are some side effects of anti-cholinergic drugs?
A
Confusion Hallucinations Tachycardia Constipation Dizziness Falls
2
Q
Give some examples of anti-cholinergic drugs
A
Oxybutynin Parkinson's drugs Antidepressants Anti-emetics Opiates Antipsychotics Antihistamines
3
Q
Why is polypharmacy important in the anti-cholinergic burden?
A
As drugs on their own will have a small anti-cholinergic effect but when combined it can increase
4
Q
What drug combination can cause postural hypotension?
A
Alpha blockers and antihypertensives
5
Q
What drug combination can cause renal failure?
A
ACE inhibitors
Trimethoprim/co-trimoxazole
6
Q
What is the definition of the number needed to treat?
A
The theoretical number of patients that get the drug that will get the benefit
7
Q
What is the definition of the number needed to harm?
A
The theoretical number of patients that get the drug that will get harm from the drug
