Preparing IV Medications

Question 1

List six main drugs + others with leaching/adsorption/absorption issues with PVC containers (hint: LATTIN)

Answer 1

1. Lorazepam
2. Amiodarone
3. Tacrolimus
4. Taxanes (except: paclitaxel-albumin bound)
5. Insulin
6. Nitroglycerin
7. others (carmustine, ixabepilone, sulfentanil, temsirolimus, teniposide, thiopental)

Question 2

List seven drugs + others that must be put in saline (no dextrose) (hint: ACID APE)

Answer 2

1. Ampicillin
2. Caspofungin (Cancidas)
3. Infliximab (Remicade)
4. Daptomycin (Cubicin)
5. Ampicillin/Sulbactam (Unasyn)
6. Phenytoin
7. Ertapenem (Invanz)
8. other (abatacept, azacitidine, belimumab, bevacizumab, idarucizumab, iron sucrose, sodium ferric gluconate complex, natalizumab, trastuzumab)

Question 3

List four main drugs + others that must be put in dextrose (no saline) (hint: BOAS)

Answer 3

1. Bactrim
2. Oxaliplatin
3. Amphotericin B (all)
4. Synercid (Quinupristin/dalfopristin)
5. others (carfilzomib, mycophenolate [CellCept IV], Pentamidine)

Question 4

List four high-risk incompatibilities with risk of precipitate

Answer 4

1. ceftriaxone and calcium
2. calcium and phosphate
3. amphotericin B and sodium bicarbonate high risk
4. lactated ringer contaisn calcium

Question 5

List three filter sizes and rank from most common to least common

Answer 5

1. 0.22 micron - most common
2. 1.2 micron - lipid emulsions
3. 5 micron - amphotericin B (lipid)

Question 6

List seven drugs + others that require a filter when administered (Hint: Thats my GAL, PLAT)

Answer 6

1. Golimumab (Symponi)
2. Amiodarone
3. Lorazepam
4. Phenytoin
5. Lipids
6. Amphotericin B (lipid formulations)
7. Taxanes (except: docetaxel)
8. others (abatacept, abciximab, infliximab, isavuconazonium, mannitol, thiotepa, some albumin products)

Question 7

List seven drugs + others that are Do Not Refrigerate (Hint: Dear Sweet Pharmacist, Marry Me – Forever, Eternally! DSPMMFE)

Answer 7

1. dexmedetomidine (precedex)
2. sulfamethoxazole/trimethorpim (Bactrim)
3. phenytoin
4. metronidazole
5. moxifloxacin (Avelox)
6. furosemide
7. enoxaparin
8. Others (acetaminophen, acyclovir, deferoxamine, levetiracetam, pentamidine, valproate)

Question 8

List five drugs + others that are Protect From Light During Administration (Hint: Deliver Every Needed Medication with a light-Protected cover DENMP)

Answer 8

1. Doxycycline
2. Epoprostenol (Flolan)
3. Nitroprusside (Nitropress)
4. Micafungin (Mycamine)
5. Phytonadione (Vitamin K; Mephyton)
6. others (Ampho B deoxycholate, anthracyclines, dacarbazine, thiotepa, pentamidine)