Preparation of Nitro Compounds Flashcards
- Which of the following is used as a reactant for the
nitration of benzene to form nitrobenzene?
a) HNO2
b) HNO3
c) Mixture of HNO2 AND HNO3
d) Mixture of HNO2 and H2SO4
c) Mixture of HNO2 AND HNO3
- In Ter Meer reaction, a method of preparation of nitro
compound, which of the following used as reagent?
a) HNO2
b) HNO3
c) NaNO2
d) RX (alkyl halide)
c) NaNO2
- What will be the product if 1,1-halonitroalkane
undergoes nucleophilic aliphatic substitution reaction in
presence of ethanol?
a) 1,1-dinitro dimer
b) 1,2-dinitro dimer
c) 1.-nitro compound
d) 2-nitrocompound
a) 1,1-dinitro dimer
- What will be the product if 1,1-halonitroalkane
undergoes nucleophilic aliphatic substitution reaction in
presence of potassiam hydroxide?
a) 1,1-dinitro dimer
b) 1,2-dinitro dimer
c) 1.-nitro compound
d) 2-nitrocompound
b) 1,2-dinitro dimer
- Which of the following is not a natural occurring nitro
compound?
a) Chloramphenicol
b) 2-Nitrophenol
c) 3-Nitropropionic acid
d) nitrobenzene
d) nitrobenzene
- Which combination of reagents used in the indicated
order with benzene will give m-nitropropylbenzene?
a) 1) HNO3/H2SO4, 2) CH3CH2CH2Cl/AlCl3
b) 1) CH3CH2CH2Cl/AlCl3, 2) HNO3/H2SO4
c) 1) CH3CH2COCl/AlCl3, 2) HNO3/H2SO4, 3) H2NNH2/NaOH
d) 1) HNO3/H2SO4, 2) CH3CH2COCl/AlCl3, 3) H2NNH2/NaOH
d) 1) HNO3/H2SO4, 2) CH3CH2COCl/AlCl3, 3) H2NNH2/NaOH
- Nitration of furan using acetyl nitrate also leads to a 2,5
addition product. How can this competing process be
suppressed?
a) By using concentrated nitric and sulfuric acids instead of
acetyl nitrate
b) By carrying out the reaction at higher temperatures
c) By carrying out the nitration in the presence of pyridine
d) By using nitric acid instead of acetyl nitrate
c) By carrying out the nitration in the presence of pyridine
- The phenomenon or process by which imine are
converted into enamine is which of the following?
a) Imination
b) Enamination
c) Amination
d) Tautomerism
d) Tautomerism
- Which of the following is not true about enamines?
a) Enamine are derived by the condensation of an
aldehyde or ketone with a primary amine
b) Enamines are versatile intermediates
c) Enamines are considered to be nitrogen analogs of enols
d) They are tautomeric form of imine
a) Enamine are derived by the condensation of an
- Enamine shows which type of behavior?
a) Basic
b) Electrophilic and acidic
c) Nucleophilic and basic
d) Nucleophilic
c) Nucleophilic and basic
- What is the name of the compound formed when
alkylation of enamine is followed by hydrolysis?
a) Carboxylic acid
b) Ketone
c) Amide
d) ester
b) Ketone
- Which cyclic ketone enamine is most reactive?
a) Five membered
b) Six membered
c) Seven membered
d) Eight membered
a) Five membered
- Compounds which have different arrangements of
atoms in space while having same atoms bonded to each
other are said to have
a) position isomerism
b) functional group isomerism
c) chain isomerism
d) stereoisomerism
d) stereoisomerism
- Which of the following can make difference in optical
isomers?
a) heat
b) temperature
c) polarized light
d) pressur
c) polarized light
- Which of the following is an alkane which can exhibit
optical activity?
a) Neopentane
b) Isopentane
c) 3–Methylpentane
d) 3–Methylhexane
d) 3–Methylhexane
- What is the molecular formula for the alkane of smallest
molecular weight which possesses a stereogenic center?
a) C4H10
b) C5H12
c) C6H14
d) C7H16
d) C7H16
- Which of the following statements most accurately
describes the stereochemistry between the various
cyclohexanes?
a) Cis-1,2-dichlorocyclohexane and trans-1,2
dichlorocyclohexane rotate plane-polarized light in
opposite directions, and together in equal proportions
form a racemic mixture
b) The diaxial and diequatorial forms of trans-1,3
dichlorohexane can be separated by their differing
physical properties
c) Only cis-1,4-dichlorocyclohexane is achiral due to a
plane of symmetry, and cis-1,4-dichlorocyclohexane is
diastereomeric to trans-1,4-dichlorocyclohexane
d) The conformational isomers of trans-1,2
dichlorocyclohexane are enantiomers, which are not
interconvertible, but resolvable
d) The conformational isomers of trans-1,2
dichlorocyclohexane are enantiomers, which are not
interconvertible, but resolvable
- How many stereoisomers of 3-bromo-2-butanol,
CH3CH(OH)CHBrCH3, exist?
a) 3
b) 1
c) 2
d) 4
d) 4
- How many stereoisomers of 2,3-butanediol,
CH3CH(OH)CH(OH)CH3, exist?
a) 3
b) 4
c) 1
d) 2
a) 3
- Which of the following compounds can exhibit
geometrical isomerism?
a) 1-Hexene
b) 2-Methyl-2-Pentene
c) 3-methyl-1-pentene
d) 2-Hexene
d) 2-Hexene
- How many number of stereoisomers possible for 2, 3
pentanediol?
a) 3
b) 4
c) 5
d) 6
b) 4
- How many chiral stereoisomers can be drawn for
CH3CHFCHFCH(CH3)2?
a) 4
b) 5
c) 6
d) 7
a) 4
- What is the total number of isomers, stereoisomers
included, designated by the dichlorocyclopentane?
a) 7
b) 6
c) 4
d) 5
a) 7
- What does a polarimeter measure?
a) Polarity of the substance
b) Angle of rotation of an optical active compound
c) Concentration of the substance
d) pH of the substance
b) Angle of rotation of an optical active compound
- A solution of 0.1 g/mL of a pure R enantiomer in a 1.0
dm (i.e., 10 cm) polarimeter rotates plane polarized light
by +4.8°. What is the rotation observed on this solution in
a 2 dm polarimeter?
a) +2.4°
b) +4.8°
c) +19°
d) +9.6
d) +9.6
- Polarimeter works on the principle of which of the
following?
a) polarisation of light
b) change of the electrical conductivity of solution with
composition
c) change of angle of refraction with composition
d) change of electrical conductivity of solution with
temperature
a) polarisation of light
- What is the effect of the I on the specific optical rotation
(α), if I gets double?
a) α gets double
b) α gets halved
c) α gets four times
d) α eight times
a) α gets double
- If a solution of a compound (30.0 g/100 mL of solution)
has a measured rotation of +15° in a 2 dm tube, what is
the specific rotation?
a) +50°
b) +25°
c) +15°
d) +7.5°
b) +25°
- Which of the following groups has the highest priority
according to the Cahn-Ingold-Prelog sequence rules?
a) CH3
b) CH2Cl
c) CH2OH
d) CHO
b) CH2Cl
- What is the percent composition of a mixture of (S)-(+)
2-butanol, α= +13.52°, and (R)-(-)-2-butanol, α = -13.52°,
with a specific rotation α = +6.76°?
a) 75%(R) 25%(S)
b) 25%(R) 75%(S)
c) 50%(R) 50%(S)
d) 67%(R) 33%(S)
b) 25%(R) 75%(S)
- What can be said with certainty if a compound has α=
9.25°?
a) The compound has the (S) configuration
b) The compound has the (R) configuration
c) The compound is not a meso form
d) The compound possesses only one stereogenic center
c) The compound is not a meso form
- Which of these is a comparatively insignificant factor
affecting the magnitude of specific optical rotation?
a) Concentration of the substance of interest
b) Purity of the sample
c) Temperature of the measurement
d) Length of the sample tube
c) Temperature of the measurement
- What is the specific optical rotation of (S)-malic acid at
a concentration of 5.5 g/ mL in the solvent pyridine at 20°C
at a wavelength of 589 nm?
a) the specific rotation is –27°
b) the specific rotation is +27°
c) the specific rotation is –17°
d) the specific rotation is +17
a) the specific rotation is –27°
- Which of the following is the definition for
enatiomerism?
a) A pair of stereoisomers each of which has two chirality
centres
b) A pair of stereoisomers that are not mirror images of
one another
c) A pair of stereoisomers that are non-superimposable
mirror images of one another
d) Any pair of stereoisomers
c) A pair of stereoisomers that are non-superimposable
mirror images of one another
- Which of the following statements is not true regarding
pairs of enantiomers?
a) They have identical boiling points
b) They rotate plane polarized light in opposite directions
c) They react at identical rates with chiral reagents
d) They have identical melting points
b) They rotate plane polarized light in opposite directions
- Which of the following statements regarding optical
rotation is not true?
a) All R enantiomers are dextrorotatory
b) All (+) enantiomers are laevorotatory
c) All (-) enantiomers rotate plane polarized light in a
counter clockwise direction
d) (+) and (-) enantiomers rotate plane polarized light in
opposite directions
c) All (-) enantiomers rotate plane polarized light in a
counter clockwise direction
- Which of the following notations is not used to
distinguish between pairs of enantiomers?
a) R and S
b) E and Z
c) + and –
d) D and L
b) E and Z
- Which among the following is true about
enantiomerism?
a) Assignments of R and S labels and (+) and (–) labels are
not connected
b) The labels R and S refer to different conformers
c) The labels (+) and (–) are used to distinguish
enantiomers
d) The specific rotation of enantiomers is equal and
opposite
b) The labels R and S refer to different conformers