Prenatal lab testing

Question 1

1st trimester lab tests(9)

Answer 1

1. CBC:Hg, Hct, MCV, Platelets, WBC
2. Rubella IgG ab
3. HepB
4. Type, Rh, Antibody screen
5. STD: chla, gon, syphlius(RPR/VDRL)
6. Urine Screening
7. TB
8. HIV
9. Pap smear

Question 2

whats the best indicator of true anemia in pregnant women? what is the usual cause?

Answer 2

MCV! usually due ot iron def

Question 3

prego women lacks rubella ab. what do you do?

Answer 3

advise to avoid travel to places w/rubella & vaccinate AFTER delivery as it is a live vaccine

Question 4

Mothers blood type is A-. why is this important?

Answer 4

she lacks the Rh surface antigen so she has antibodies to the surface antigen and will need rogam @ delivery + follow up testing

Question 5

mother is + for syphilis. what do you do?

Answer 5

treat her w/ penicillin

Question 6

mother is + for PPD test. how do you work this up?

Answer 6

CXR! if + treat w/triple therapy(RIPE) if negative treat w/9 months of INH + B6

Question 7

Who gets an HIV test w/prego?

Answer 7

ALL unless they opt out.

Question 8

2nd trimester testing(2)

Answer 8

1. MS-AFP - peaks in fetus @12 wks and in mom @30 wks; elevated in NTD
2. Quadruple marker Screening(MSAFP, Estriol, hCG, Inhibin)

Question 9

What does an elevated AF Acetylcholinesterase tell you?

Answer 9

specific for open NTD!

Question 10

Low MS-AFP(0.75) is indicative of…

Answer 10

trisomy 21

Question 11

MS-AFP of 1 is indicative of…

Answer 11

normal!

Question 12

elevated MS-AFP(3.8) is indicative of…

Answer 12

open NTD

Question 13

High MS-AFP(7.7) is indicative of…

Answer 13

Anencephaly

Question 14

Quad screening shows: decreased MS-AFP & Estriol but elevated hCG & Inhibin-A this corresponds w/….

Answer 14

Trisomy 21! DS!

Question 15

Quad screening shows: decreased MS-AFP, Estriol, hCG & Inhibin-A this corresponds w/….

Answer 15

Trisomy 18! Edwards Syndrome

Question 16

3rd trimester screening tests

Answer 16

1. Diabetes
2. CBC
3. Atypical Antibody Testing